Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Magnetic nanosystem for cancer therapy using oncocalyxone a, an antitomour secondary metabolite isolated from a Brazilian plant.
A. C. H. Barreto,Vivian Romero Santiago,Rafael M. Freire,Selma Elaine Mazzetto,Juliano C. Denardin,Giuseppe Mele,Igor Marques Cavalcante,Maria Elenir Nobre Pinho Ribeiro,Nágila M.P.S. Ricardo,Tamara Gonçalves,Luigi Carbone,Telma L. G. Lemos,Otília Deusdênia L. Pessoa,Pierre Basílio Almeida Fechine +13 more
TL;DR: The results found in this work showed the potential of onco A for future applications of the MO-20 as a new magnetic drug release nanosystem for cancer treatment.
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Reduced transdermal absorption of N,N-diethyl-m-toluamide from a new topical insect repellent formulation.
TL;DR: FA exhibited reduced in vitro skin permeation and in vivo transdermal absorption of DEET as well as superior repellency compared with FB, and the PEG-polyacrylic acid polymer system is of value in the formulation ofDEET lotions.
Journal ArticleDOI
Development of Duloxetine Hydrochloride Loaded Mesoporous Silica Nanoparticles: Characterizations and In Vitro Evaluation
TL;DR: The results supported the efficacy of mesoporous silica nanoparticles synthesized here as a promising carrier for duloxetine hydrochloride with higher drug loading and greater pH-sensitive release.
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Validation of kinetic modeling of progesterone release from polymeric membranes.
Analía I. Romero,Mercedes Villegas,Alicia Graciela Cid,Monica Liliana Parentis,Elio Emilio Gonzo,José María Bermúdez +5 more
TL;DR: In this article, a mathematical model that describes progesterone controlled release from poly-3-hydroxybutyric acid (PHB) membranes was proposed and a statistical analysis was conducted to compare the fitting of the model with six different models and the Akaike information criterion (AIC) was used to find the equation with best fit.
Journal ArticleDOI
Effect of natural and synthetic surfactants on polysaccharide nanoparticles: Hydrophobic drug loading, release, and cytotoxic studies
TL;DR: In this paper, the effects of Triton X-100 and saponin, a natural surfactant extracted from Sapindus rarak on the modification of cellulose and starch nanoparticles were investigated during hydrophobic drug loading and release.