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Journal ArticleDOI

Rate of release of medicaments from ointment bases containing drugs in suspension

Takeru Higuchi
- 01 Oct 1961 - 
- Vol. 50, Iss: 10, pp 874-875
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.
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This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.

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Kinetics of Cephalexin Release from Eudragit-Hydroxypropylcellulose Membranes

TL;DR: In this article, the authors investigated the release of cephalexin dispersed in films composed of different ratios of Eudragit-RS and hydroxyropylcellulose (HPC) in a diffusion-controlled model, where the quantity released per unit area is proportional to the square roof of time.
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Formulation development of Carvedilol compression coated tablet

TL;DR: The Powder blends for core and coat tablets showed satisfactory flow properties, compressibility, drug content and all the tablet formulations showed acceptable pharmaco-technical properties.
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Terminalia Gum as a Directly Compressible Excipient for Controlled Drug Delivery

TL;DR: Terminalia gum compared favourably with standard polymers when used in controlled release matrices and could serve as a suitable alternative to the standard polymer in drug delivery.
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Storage and sustained release of volatile substances from a hollow silica matrix

TL;DR: Porous hollow silica nanospheres (PHSNSs) prepared by adopting a nanosized CaCO3 template were utilized for the first time as a novel carrier for the storage and sustained release of volatile substances as mentioned in this paper.
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