Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Superparamagnetic Reduction/pH/Temperature Multistimuli-Responsive Nanoparticles for Targeted and Controlled Antitumor Drug Delivery
TL;DR: The results suggest that the novel biodegradable nanoparticles with high drug loading capacity and multiresponsive controlled release capability could serve as an excellent gene/drug delivery system candidate for cancer therapy.
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Polymer Drugs and Polymeric Drugs X: Slow Release of 5-Fluorouracil from Biodegradable Poly(γ-Glutamic Acid) and its Benzyl Ester Matrices:
TL;DR: In this article, the degradation behavior and its usefulness as a drug delivery system (DDS) matrix using 5-fluorouracil (5-FU) as a model drug were evaluated.
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The effects of laser energy density and particle size in the selective laser sintering of polycaprolactone/progesterone specimens: morphology and drug release
TL;DR: The results showed that the specimens maintained morphological uniformity, coalescence of particles, and interconnected pores distributed in the sintered structure, and the drug release mechanism of all specimens studied followed a zero-order kinetics.
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Release kinetics and up-take studies of model fluoroquinolones from carbomer hydrogels.
Ana Paula Vilches,Alvaro F. Jimenez-Kairuz,Fabiana L. Alovero,María Eugenia Olivera,Daniel Alberto Allemandi,Ruben H. Manzo +5 more
TL;DR: Hydrogels C-AMFQ behave as a reservoir of AMFQ able to deliver it at a constant rate and would be useful to design topical and or systemic dosage forms.
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Hyperbranched Polymers as Drug Carriers: Microencapsulation and Release Kinetics
Supakij Suttiruengwong,Jörn Rolker,Irina Smirnova,Wolfgang Arlt,Matthias Seiler,L Lüderitz,Y. Pérez de Diego,Peter J. Jansens +7 more
TL;DR: The aim of this work was to study the feasibility of hyperbranched polymers as drug carriers by employing different microparticle formation methods and the influence of loading methods on release kinetics.