Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Effect of heat on the percutaneous absorption and skin retention of three model penetrants
TL;DR: The effect of heat on the transdermal delivery of model penetrants of differing lipophilicity through artificial membranes (non-rate limiting) and human epidermis was investigated in vitro and epidermal flux and retention of all penetrants was found to be affected by temperature.
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Electrosprayed gelatin submicroparticles as edible carriers for the encapsulation of polyphenols of interest in functional foods
TL;DR: In this paper, the potential of the electrospraying technique to obtain food-grade gelatin capsules in the submicron range for sensitive bioactive protection was explored, studying the influence of the protein concentration on the size and morphology of the obtained particles.
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A Sustained Release Drug Delivery System Using Calcium Alginate Beads
TL;DR: In this article, the authors used scanning electron microscopy to examine the surface of the beads with and without sulphamethoxazole as a model drug and found that the release behavior was a function of calcium chloride concentration.
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Surfactant-laden soft contact lenses for extended delivery of ophthalmic drugs.
TL;DR: Developing surfactant-laden poly-hydroxy ethyl methacrylate contact lenses that can release Cyclosporine A at a controlled rate for extended periods of time and possess suitable mechanical and optical properties for contact lens applications are studied.
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Hydroxypropyl methylcellulose-based controlled release dosage by melt extrusion and 3D printing: Structure and drug release correlation
TL;DR: This work reports the successful fabrication of solid-dispersion filaments with an API dispersed in HPMC based matrix via HME technology, and the production of zero order controlled release tablets with different 3D structures using a 3D printer.