The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
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TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
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Challenges in the diagnosis and management of vitreoretinal lymphoma – Clinical and basic approaches
Hiroshi Takase,Ayako Arai,Yuko Iwasaki,Ayano Imai,Toshikage Nagao,Masahiko Kawagishi,Tomoka Ishida,Manabu Mochizuki +7 more
TL;DR: In this article , the authors discuss the use of immunological, molecular, and gene analyses using intraocular samples to diagnose vitreoretinal lymphoma (VRL) in diffuse large B-cell lymphoma.
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Mantle cell lymphoma: therapeutic options in transplant-ineligible patients.
TL;DR: Novel targeted agents now offer more promise than traditional chemotherapy or immunochemotherapy for both previously treated and untreated disease, and should also improve outcomes for older MCL patients.
Journal ArticleDOI
Posttransplant lymphoproliferative disorder in pediatric patients: Survival rates according to primary sites of occurrence and a proposed clinical categorization.
Arnaud G L'Huillier,Anne I. Dipchand,Vicky L. Ng,Diane Hebert,Yaron Avitzur,Melinda Solomon,Bo-Yee Ngan,Derek Stephens,Angela Punnett,Michelle Barton,Michelle Barton,Upton Allen +11 more
TL;DR: A clinical categorization of PTLD according to anatomical site of occurrence is proposed and T/A PTLD was associated with a survival advantage compared with PTLD at other sites, even after adjustment for potential confounders.
Journal ArticleDOI
Allogeneic Stem Cell Transplantation Provides Durable Remission in Patients with Primary Mediastinal Large B Cell Lymphoma.
Alex F. Herrera,Lu Chen,Sirin Khajavian,Matthew L Chase,Justin Darrah,David G. Maloney,David G. Maloney,Vincent T. Ho,Robert J. Soiffer,Joseph H. Antin,Stephen J. Forman,Auayporn Nademanee,Yi Bin Chen,Philippe Armand,Mazyar Shadman,Mazyar Shadman +15 more
TL;DR: In a multicenter retrospective study, alloHSCT produced durable remissions in a proportion of patients with treatment-sensitive disease prior to transplantation (5-year PFS 44%) and should be considered in the treatment of patientswith rel/ref PMBCL.
Journal ArticleDOI
Clonal approaches to understanding the impact of mutations on hematologic disease development.
TL;DR: How clonal approaches have advanced the authors' understanding of disease development is reviewed, focusing on the acquisition of somatic mutations, clonal selection, driver mutation cooperation, and tumor evolution.
References
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Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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