The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
Reads0
Chats0
TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
More filters
Journal ArticleDOI
Brentuximab vedotin followed by bendamustine supercharge for refractory or relapsed Hodgkin lymphoma.
Marco Picardi,R. Della Pepa,Claudia Giordano,Novella Pugliese,Chiara Mortaruolo,Fabio Trastulli,M.G. Rascato,I. Cappuccio,Marta Raimondo,M. Memoli,Maria Monteverde,Massimo Mascolo,Fabrizio Pane +12 more
TL;DR: The data suggest that Bv+Bs regimen-driven strategy may be a promising salvage option to improve long-term control of high-risk Hodgkin lymphoma.
Journal ArticleDOI
Composite and sequential lymphoma between classical Hodgkin lymphoma and primary mediastinal lymphoma/diffuse large B-cell lymphoma, a clinico-pathological series of 25 cases.
Guillaume Aussedat,Alexandra Traverse-Glehen,Aspasia Stamatoullas,Thierry Jo Molina,Violaine Safar,Camille Laurent,Jean-Marie Michot,Pierre Hirsch,Emmanuelle Nicolas-Virelizier,Sylvain Lamure,Caroline Regny,Jean-Michel Picquenot,Albane Ledoux-Pilon,Patrick Tas,Catherine Chassagne-Clément,Guillaume Manson,Richard Lemal,Juliette Fontaine,Marie Le Cann,Gilles Salles,Hervé Ghesquières,Christiane Copie-Bergman,Clémentine Sarkozy +22 more
TL;DR: A retrospective analysis describes the pathological and clinical characteristics of 10 composite and 15 sequential lymphomas involving both classical Hodgkin lymphoma and primary mediastinal B‐cell lymphoma included after a central pathological review.
Journal ArticleDOI
Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL)
Xin Xu,Xin Xu,Matko Kalac,Michael Markson,Mark Chan,Joshua Brody,Govind Bhagat,Rosalind L. Ang,Diana Legarda,Scott J. Justus,Feng Liu,Qingshan Li,Huabao Xiong,Adrian T. Ting,Adrian T. Ting +14 more
TL;DR: CYLD is identified as a crucial regulator of ATLL survival and point to its role as a potential novel target for pharmacologic modification in this disease.
Journal ArticleDOI
Prediction and prevention of central nervous system relapse in patients with extranodal natural killer/T-cell lymphoma
Hyera Kim,Hyera Kim,Hyehyun Jeong,Motoko Yamaguchi,Insuk Sohn,Sang Eun Yoon,Seonggyu Byeon,Joon Young Hur,Joon Young Hur,Youngil Koh,Sung Soo Yoon,Eo Jin Kim,Masahiko Oguchi,Kana Miyazaki,Senzo Taguchi,Dok Hyun Yoon,Junhun Cho,Young Hyeh Ko,Seok Jin Kim,Ritsuro Suzuki,Won Seog Kim +20 more
TL;DR: The CNS-PINK was demonstrated its strong predictability of CNS relapse in ENKTL patients and the necessity of CNS prophylaxis with intermediate-dose MTX (ID-MTX) should be verified by future studies.
Journal ArticleDOI
A novel prognostic model based on four circulating miRNA in diffuse large B-cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression.
Rui Sun,Zhong Zheng,Li Wang,Shu Cheng,Qing Shi,Bin Qu,Di Fu,Christophe Leboeuf,Yan Zhao,Jing Ye,Anne Janin,Wei-Li Zhao +11 more
TL;DR: The novel 4‐circulating miRNA prognostic model significantly predicted clinical outcome of DLBCL, independent of International Prognostic Index in the training cohort and in the validation cohort, and effectively predicted relapse and survival inDLBCL.
References
More filters
Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
Related Papers (5)
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray
Christine P. Hans,Dennis D. Weisenburger,Timothy C. Greiner,Randy D. Gascoyne,Jan Delabie,German Ott,H. Konrad Muller-Hermelink,Elias Campo,Rita M. Braziel,Elaine S. Jaffe,Zenggang Pan,Pedro Farinha,Lynette M. Smith,Brunangelo Falini,Alison H. Banham,Andreas Rosenwald,Louis M. Staudt,Joseph M. Connors,James O. Armitage,Wing C. Chan +19 more
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Ash A. Alizadeh,Michael B. Eisen,R. Eric Davis,Izidore S. Lossos,Andreas Rosenwald,Jennifer C. Boldrick,Hajeer Sabet,Truc Tran,Xin Yu,John Powell,Liming Yang,Gerald E. Marti,Troy Moore,James I. Hudson,Li-Sheng Lu,David B. Lewis,Robert Tibshirani,Gavin Sherlock,Wing C. Chan,Timothy C. Greiner,Dennis D. Weisenburger,James O. Armitage,Roger A. Warnke,Ronald Levy,Wyndham H. Wilson,M. R. Grever,John C. Byrd,David Botstein,Patrick O. Brown,Louis M. Staudt +29 more