The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
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Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study.
Jeremy S. Abramson,M. Lia Palomba,Leo I. Gordon,Matthew A. Lunning,Michael Wang,Jon E. Arnason,Amitkumar Mehta,Enkhtsetseg Purev,David G. Maloney,Charalambos Andreadis,Alison R. Sehgal,Scott R. Solomon,Nilanjan Ghosh,Tina Albertson,Jacob Garcia,Ana Kostic,Mary Mallaney,Ken Ogasawara,Kathryn Newhall,Yeonhee Kim,Daniel Li,Tanya Siddiqi +21 more
TL;DR: Overall safety and activity of liso-cel did not differ by dose level, with a high objective response rate, and a low incidence of grade 3 or worse cytokine release syndrome and neurological events in patients with relapsed or refractory large B-cell lymphomas.
Journal ArticleDOI
Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis
TL;DR: The cancer burden attributed to human papillomavirus showed the clearest relationship with country income level, and infection-attributable cancer incidence allows for refined geographic analyses and identification of populations with a high infection-associated cancer burden.
Journal ArticleDOI
2016 US lymphoid malignancy statistics by World Health Organization subtypes.
Lauren R. Teras,Carol DeSantis,James R. Cerhan,Lindsay M. Morton,Ahmedin Jemal,Christopher R. Flowers +5 more
TL;DR: Estimates of the total numbers of US lymphoid neoplasm cases by subtype as well as a detailed evaluation of incidence and survival statistics are presented, which can offer clues regarding their etiology.
Journal ArticleDOI
Infection in Organ Transplantation
TL;DR: Transplant infectious disease remains a key to the clinical and scientific investigation of organ transplantation and application of quantitative molecular microbial assays and advanced antimicrobial therapies have advanced care.
Journal ArticleDOI
International Consensus Classification of Myeloid Neoplasms and Acute Leukemia: Integrating Morphological, Clinical, and Genomic Data.
Daniel A. Arber,Attilio Orazi,Robert P. Hasserjian,Michael Horowitz,Katherine R. Calvo,Hans Michael Kvasnicka,Sa A. Wang,Adam Bagg,Tiziano Barbui,Susan Branford,Carlos E. Bueso-Ramos,Jorge E. Cortes,Paola Dal Cin,Courtney D. DiNardo,Hervé Dombret,Eric J. Duncavage,Benjamin L. Ebert,Elihu H. Estey,Fabio Facchetti,Kathryn Foucar,Naseema Gangat,Umberto Gianelli,Lucy A. Godley,Nicola Goekbuget,Jason Gotlib,Eva Hellström-Lindberg,Gabriela S. Hobbs,Roald Hoffmann,Elias Jabbour,Jean-Jacques Kiladjian,Richard A. Larson,Michelle M. Le Beau,Mignon L. Loh,Bob Löwenberg,Elizabeth Macintyre,Luca Malcovati,Charles G. Mullighan,Charlotte M. Niemeyer,Olatoyosi Odenike,Seishi Ogawa,Alberto Orfao,Elli Papaemmanuil,Francesco Passamonti,Kimmo Porkka,C H Pui,Jerald P. Radich,Andreas Reiter,María Rozman,Martina Rudelius,Michael R. Savona,Charles A. Schiffer,Annette Schmitt-Graeff,Akiko Shimamura,Jorge Sierra,Wendy Stock,Richard Stone,Martin S. Tallman,Juergen Thiele,Hwei-Fang Tien,Alexandar Tzankov,Alessandro M. Vannucchi,Paresh Vyas,Andrew H. Wei,Olga Weinberg,Agnieszka Wierzbowska,Mario Cazzola,Hartmut Döhner,Ayalew Tefferi +67 more
TL;DR: The authors, a group with expertise in the clinical, pathologic and genetic aspects of these disorders, developed the International Consensus Classification (ICC), aimed at facilitating diagnosis and prognostication of these neoplasms, improving treatment of affected patients, and allowing the design of innovative clinical trials.
References
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SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
Lili Wang,Michael S. Lawrence,Youzhong Wan,Petar Stojanov,Carrie Sougnez,Kristen E. Stevenson,Lillian Werner,Andrey Sivachenko,David S. DeLuca,Li Zhang,Wandi Zhang,Alexander R. Vartanov,Stacey M. Fernandes,Natalie R. Goldstein,Eric G. Folco,Kristian Cibulskis,Bethany Tesar,Quinlan L. Sievers,Erica Shefler,Stacey Gabriel,Nir Hacohen,Robin Reed,Matthew Meyerson,Todd R. Golub,Eric S. Lander,Donna Neuberg,Jennifer R. Brown,Gad Getz,Catherine J. Wu +28 more
TL;DR: This study defines the landscape of somatic mutations in chronic lymphocytic leukemia and highlights pre-mRNA splicing as a critical cellular process contributing to chronic lymphocrytic leukemia.
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Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia.
Víctor Quesada,Laura Conde,Neus Villamor,Gonzalo R. Ordóñez,Pedro Jares,Laia Bassaganyas,Andrew J. Ramsay,Sílvia Beà,Magda Pinyol,Alejandra Martínez-Trillos,Mónica López-Guerra,Dolors Colomer,Alba Navarro,Tycho Baumann,Marta Aymerich,María Rozman,Julio Delgado,Eva Giné,Jesús M. Hernández,Marcos González-Díaz,Diana A. Puente,Gloria Velasco,José M.P. Freije,Jose M. C. Tubio,Romina Royo,Josep Lluís Gelpí,Modesto Orozco,David G. Pisano,Jorge Zamora,Miguel Vazquez,Alfonso Valencia,Heinz Himmelbauer,Mònica Bayés,Simon Heath,Marta Gut,Ivo Gut,Xavier Estivill,Armando López-Guillermo,Xose S. Puente,Elias Campo,Carlos López-Otín +40 more
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A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling
Michael Hummel,Stefan Bentink,Hilmar Berger,Wolfram Klapper,Swen Wessendorf,Thomas F. E. Barth,Heinz Wolfram Bernd,Sergio Cogliatti,Judith Dierlamm,Alfred C. Feller,Martin-Leo Hansmann,Eugenia Haralambieva,Lana Harder,Dirk Hasenclever,Michael Kühn,Dido Lenze,Peter Lichter,José I. Martín-Subero,Peter Möller,Hans Konrad Müller-Hermelink,German Ott,Reza Parwaresch,Christiane Pott,Andreas Rosenwald,Maciej Rosolowski,Carsten Schwaenen,Benjamin Stürzenhofecker,Monika Szczepanowski,Heiko Trautmann,Hans Heinrich Wacker,Rainer Spang,Markus Loeffler,Lorenz Trümper,Harald Stein,Reiner Siebert +34 more
TL;DR: The molecular definition of Burkitt's lymphoma clarifies and extends the spectrum of the WHO criteria for Burkitt’s lymphoma.
SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
Lili Wang,Michael S. Lawrence,Youzhong Wan,Petar Stojanov,Carrie Sougnez,Kristen E. Stevenson,Lillian Werner,Andrey Sivachenko,David S. DeLuca,Li Zhang,Wandi Zhang,Alexander R. Vartanov,Stacey M. Fernandes,Natalie R. Goldstein,Eric G. Folco,Kristian Cibulskis,Bethany Tesar,Quinlan L. Sievers,Erica Shefler,Stacey Gabriel,Nir Hacohen,Robin Reed,Matthew Meyerson,Todd R. Golub,Eric S. Lander,Donna Neuberg,Jennifer R. Brown,Gad Getz,Catherine J. Wu +28 more
TL;DR: In this article, the authors proposed a method to detect the presence of cancer in the human genome using the Human Genome Research Institute (HGRI) grant U54HG003067.
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BRAF mutations in hairy-cell leukemia
Enrico Tiacci,Vladimir Trifonov,Gianluca Schiavoni,Antony B. Holmes,Wolfgang Kern,Maria Paola Martelli,Alessandra Pucciarini,Barbara Bigerna,Roberta Pacini,Victoria A. Wells,Paolo Sportoletti,Valentina Pettirossi,Roberta Mannucci,Oliver Elliott,Arcangelo Liso,Achille Ambrosetti,Alessandro Pulsoni,Francesco Forconi,Livio Trentin,Gianpietro Semenzato,Giorgio Inghirami,Monia Capponi,Francesco Di Raimondo,Caterina Patti,Luca Arcaini,Pellegrino Musto,Stefano Pileri,Claudia Haferlach,Susanne Schnittger,Giovanni Pizzolo,Robin Foà,Laurent Farinelli,Torsten Haferlach,Laura Pasqualucci,Raul Rabadan,Brunangelo Falini +35 more
TL;DR: The BRAF V600E mutation was present in all patients with HCL who were evaluated, and may have implications for the pathogenesis, diagnosis, and targeted therapy of HCL.
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