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Open AccessJournal ArticleDOI

The 2016 revision of the World Health Organization classification of lymphoid neoplasms

TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.
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This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.

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The Evolution of Breast Implants.

TL;DR: The history of breast implants since their invention in 1962 is discussed, with particular emphasis given to the evolution of silicone implants with its many challenges, which has resulted in the development of the currently used fourth- and fifth-generation devices.
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Clinicopathological Study of 30 Cases of Peripheral T-cell Lymphoma with Hodgkin and Reed-Sternberg-like B-cells from Japan.

TL;DR: HRS-like B-cells were found in a subset of T-cell lymphomas, especially in association with the TFH phenotype and EBV reactivation, which has a tendency to affect elderly patients and to be associated with advanced clinical stages and dismal prognosis.
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Low Humoral Immune Response and Ineffective Clearance of SARS-Cov-2 in a COVID-19 Patient With CLL During a 69-Day Follow-Up

TL;DR: Considering the low humoral immune response and ineffective clearance of SARS-Cov-2 in CLL patients, the follow-up and home quarantine period should be extended.
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Treatment of relapsed/refractory paediatric aggressive B‐cell non‐Hodgkin lymphoma

TL;DR: In this paper, the authors proposed a new standard of care for aggressive B-cell non-Hodgkin lymphoma (B-NHL) in children/adolescents.
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BCL6 locus is hypermethylated in angioimmunoblastic T-cell lymphoma.

TL;DR: Deregulated BCL6 expression caused by hypermethylation and TET2 mutations may result in skewed TFH differentiation and eventually contribute to AITL/PTCL development in patients, as well as lymphoma development in Tet2 knockdown mice.
References
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Book

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues

TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
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The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.

TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
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MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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