The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
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The 2017 WHO update on mature T- and natural killer (NK) cell neoplasms.
TL;DR: The 2017 WHO classification of haematopoietic and lymphoid tumours is not a new edition but an update and revision of the 4th edition, with major changes in the designation and definition of already established entities.
Journal ArticleDOI
Peripheral nervous system involvement in lymphomas
Chiara Briani,Andrea Visentin,Marta Campagnolo,Alessandro Salvalaggio,Sergio Ferrari,Tiziana Cavallaro,Renzo Manara,Roberto Gasparotti,Francesco Piazza +8 more
TL;DR: The peripheral nervous system may be involved at any stage in the course of lymphoproliferative diseases and some clinical findings, such a focal or diffuse involvement, symmetric or asymmetric pattern, presence of pain may point to the correct diagnosis.
Journal ArticleDOI
Cohort Profile: The Haematological Malignancy Research Network (HMRN): a UK population-based patient cohort.
Alexandra Smith,Debra Howell,Simon Crouch,Daniel Painter,John Blase,Han-I Wang,Ann Hewison,Timothy Bagguley,Simon Appleton,Sally E. Kinsey,Cathy Burton,Russell Patmore,Eve Roman +12 more
TL;DR: Cohort Profile: The Haematological Malignancy Research Network (HMRN): a UK populationbased patient cohort Alexandra Smith, Debra Howell, Simon Crouch, Dan Painter, John Blase, Han-I Wang and Ann Hewison.
Journal ArticleDOI
Bone marrow involvement in patients with nodular lymphocyte predominant Hodgkin lymphoma.
Joseph D. Khoury,Dan Jones,Marwan A. Yared,John T. Manning,Lynne V. Abruzzo,Fredrick B. Hagemeister,L. Jeffrey Medeiros +6 more
TL;DR: A small subset of patients in whom lymph node biopsy shows nodular lymphocyte predominant Hodgkin lymphoma with a purely nodular pattern also may have lymphoma in the bone marrow, indicating the need for intensive therapy.
Journal ArticleDOI
CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages
Antonin Papin,Antonin Papin,Benoit Tessoulin,Celine Bellanger,Celine Bellanger,Anne Moreau,Yannick Le Bris,Hervé Maisonneuve,Philippe Moreau,Cyrille Touzeau,Martine Amiot,Martine Amiot,Catherine Pellat-Deceunynck,Catherine Pellat-Deceunynck,Steven Le Gouill,David Chiron,David Chiron +16 more
TL;DR: The interplay between MCL cells and the associated monocytes/macrophages is focused on and it is suggested that macrophages are a potential target for developing novel therapeutic strategies in MCL.
References
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Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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