The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
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TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
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Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies
Mette Dahl,Mette Dahl,Iben Daugaard,Maria S. Andersen,Thomas B. Hansen,Kirsten Grønbæk,Kirsten Grønbæk,Jørgen Kjems,Lasse Sommer Kristensen +8 more
TL;DR: A map of circRNA expression in B-cell malignancies based on high-throughput RNA sequencing and an enzyme-free digital counting methodology, which has the potential to become a new gold standard for circRNA quantification are provided.
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Epstein Barr Virus Associated Lymphomas and Epithelia Cancers in Humans.
TL;DR: Current updates on EBV associated epithelial and B cell-derived malignancies, and the role of EBV latency gene products in the pathogenesis of the cancers, are summarized, and areas for future studies when considering therapeutic measures are suggested.
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2021 Update on Diffuse large B cell lymphoma: A review of current data and potential applications on risk stratification and management.
TL;DR: In this paper, the authors summarized the recent data and discuss ongoing efforts to improve DLBCL treatment in the frontline and relapsed refractory settings, and evaluated risk-adapted therapy based on classification by cell of origin (COO) and molecular features.
Journal ArticleDOI
Follicular lymphoma: 2018 update on diagnosis and management
TL;DR: Follicular lymphoma is generally an indolent B cell lymphoproliferative disorder of transformed follicular center B cells that is characterized by diffuse lymphadenopathy, bone marrow involvement, splenomegaly and less commonly other extranodal sites of involvement.
Journal ArticleDOI
Randomized Phase III Study of Alisertib or Investigator's Choice (Selected Single Agent) in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma.
Owen A. O'Connor,Muhit Ozcan,Eric D. Jacobsen,Roncero Jm,Judith Trotman,Judith Trotman,Judit Demeter,Tamás Masszi,Juliana Pereira,Rod Ramchandren,Anne W. Beaven,Dolores Caballero,Steven M. Horwitz,Anne Lennard,Mehmet Turgut,Nelson Hamerschlak,Francesco d'Amore,Francine M. Foss,Won Seog Kim,John P. Leonard,P. L. Zinzani,C.S. Chiattone,Eric D. Hsi,Lorenz Trümper,Hua Liu,Sheldon-Waniga E,Claudio Dansky Ullmann,Karthik Venkatakrishnan,EJ Leonard,Andrei R. Shustov,Lumiere Study Investigators +30 more
TL;DR: In patients with relapsed/refractory PTCL, alisertib was not statistically significantly superior to the comparator arm, and the study drug discontinuation was stopped early.
References
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WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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