The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
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TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
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Pathogenic B‐cell receptor signaling in lymphoid malignancies: New insights to improve treatment
TL;DR: In this paper, the distinct roles of antigen-dependent and antigenindependent BCR signaling in different subtypes of diffuse large B-cell lymphoma (DLBCL), a common and aggressive cancer.
Journal ArticleDOI
Comprehensive review of post-organ transplant hematologic cancers.
TL;DR: A higher risk for a variety of cancers is among the major complications of posttransplantation immunosuppression, and preventive screening strategies have been attempted mainly for PTLDs.
Journal ArticleDOI
Molecular biology of Hodgkin lymphoma
Marc A. Weniger,Ralf Küppers +1 more
TL;DR: A detailed analysis of the landscape of genetic lesions in HRS cells so far did not reveal any highly recurrent HRS cell-specific lesions, but major roles of genetic lesion in members of the NF-κB and JAK/STAT pathways and of factors of immune evasion as discussed by the authors.
Journal ArticleDOI
Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) and the Textured Breast Implant Crisis
Anne Karoline Groth,Ruth Graf +1 more
TL;DR: The majority of patients can be cured, and complete capsular removal is the most important factor, but at stages II to IV, a systemic treatment is warranted, including chemotherapy, radiotherapy, and brentuximab vedotin.
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TP53 mutation and survival in aggressive B cell lymphoma
Thorsten Zenz,Markus Kreuz,Maxi Fuge,Wolfram Klapper,Heike Horn,Annette M. Staiger,Doris Winter,Hanne Helfrich,Jennifer Huellein,Martin-Leo Hansmann,Harald Stein,Alfred C. Feller,Peter Møller,Norbert Schmitz,Lorenz Trümper,Markus Loeffler,Reiner Siebert,Andreas Rosenwald,German Ott,Michael Pfreundschuh,Stephan Stilgenbauer +20 more
TL;DR: TP53 mutations are independent predictors of survival in untreated patients with aggressive CD20+ lymphoma and should be considered for risk models in DLBCL and strategies to improve outcome for patients with mutant TP53 must be developed.
References
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WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
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The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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