The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
Reads0
Chats0
TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
More filters
Journal ArticleDOI
T-cell Lymphoma Epidemiology: the Known and Unknown
TL;DR: Current epidemiologic and prognostic factors data associated with the individual subtypes both of peripheral T-cell lymphoma and cutaneous T- cell lymphoma found in large cohort and case studies are reported on.
Journal ArticleDOI
Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas
Raphael Koch,Amanda L. Christie,Amanda L. Christie,Jennifer L. Crombie,Adam C. Palmer,Deborah Plana,Kay Shigemori,Sara N. Morrow,Alexandria Van Scoyk,Wenchao Wu,Elizabeth Brem,J. Paul Secrist,Lisa Drew,Alwin Schuller,Justin Cidado,Anthony Letai,David M. Weinstock,David M. Weinstock +17 more
TL;DR: MCL1 inhibition is a promising strategy as both a single agent and in combination with chemotherapy for patients with TCL and functional dependence on MCL1 and the combination of AZD5991 and CHOP achieved synergy based on survival improvement beyond a mathematical "sum of benefits" model.
Journal ArticleDOI
The aetiology of B‐cell lymphoid malignancies with a focus on chronic inflammation and infections
TL;DR: The latest developments in the aetiology of B‐cell lymphoid malignancy subtypes focusing on immune perturbation are summarized, linking several subtypes to variations in the human leucocyte antigen (HLA) class genes.
Journal ArticleDOI
Aptamer based recognition of cancer cells: Recent progress and challenges in bioanalysis
TL;DR: This review summarizes advances from 2010 to June 2020 in the development of aptasensors for cancer cell detection, and addresses the remaining challenges and opportunities to integrate aptasensing platforms into point-of-care solutions.
Journal ArticleDOI
CLIPPERS and its mimics: evaluation of new criteria for the diagnosis of CLIPPERS
Guillaume Taieb,Patricia Mulero,Dimitri Psimaras,Bob W. van Oosten,Jorg Dieter Seebach,Romain Marignier,Fernando Pico,Valérie Rigau,Yuji Ueno,Claire Duflos,Vera Fominykh,Vincent Guiraud,Christine Lebrun-Frenay,Jean-Philippe Camdessanché,Philippe Kerschen,Guido Ahle,N. Téllez,Alex Rovira,Khê Hoang-Xuan,Jean Pelletier,Pierre Labauge +20 more
TL;DR: This study highlights that nodular enhancement should be considered more as an unusual finding than a red flag excluding the diagnosis of CLIPPERS; red flags may occur up to 18 months after disease onset; and brain biopsy should target an atypical enhancing lesion when non-invasive investigations remain inconclusive.
References
More filters
Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
Related Papers (5)
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray
Christine P. Hans,Dennis D. Weisenburger,Timothy C. Greiner,Randy D. Gascoyne,Jan Delabie,German Ott,H. Konrad Muller-Hermelink,Elias Campo,Rita M. Braziel,Elaine S. Jaffe,Zenggang Pan,Pedro Farinha,Lynette M. Smith,Brunangelo Falini,Alison H. Banham,Andreas Rosenwald,Louis M. Staudt,Joseph M. Connors,James O. Armitage,Wing C. Chan +19 more
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Ash A. Alizadeh,Michael B. Eisen,R. Eric Davis,Izidore S. Lossos,Andreas Rosenwald,Jennifer C. Boldrick,Hajeer Sabet,Truc Tran,Xin Yu,John Powell,Liming Yang,Gerald E. Marti,Troy Moore,James I. Hudson,Li-Sheng Lu,David B. Lewis,Robert Tibshirani,Gavin Sherlock,Wing C. Chan,Timothy C. Greiner,Dennis D. Weisenburger,James O. Armitage,Roger A. Warnke,Ronald Levy,Wyndham H. Wilson,M. R. Grever,John C. Byrd,David Botstein,Patrick O. Brown,Louis M. Staudt +29 more