The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
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Advances in risk assessment and prophylaxis for central nervous system relapse in diffuse large B-cell lymphoma
TL;DR: Both intrathecal and systemic strategies for prophylaxis in high-risk patients are reviewed, with a preference for systemic methotrexate in concert with standard chemoimmunotherapy in the majority of cases.
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Finding Consensus After Two Decades of Breast Implant-Associated Anaplastic Large Cell Lymphoma
Mark W. Clemens,Ryan C. DeCoster,Berry Fairchild,Alexander A. Bessonov,Fabio Santanelli di Pompeo +4 more
TL;DR: The authors focus on the early diagnosis and treatment, including reconstructing the breast following BIA-ALCL, and also discuss recently updated National Comprehensive Cancer Network guidelines, which discuss important medicolegal considerations and the bioethics surrounding the continued use of textured-surface breast implants.
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Drug Resistance in Non-Hodgkin Lymphomas.
Pavel Klener,Magdalena Klanova +1 more
TL;DR: The history and recent advances in the understanding of molecular mechanisms of resistance to genotoxic and targeted agents used in clinical practice for the therapy of NHL are focused on.
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Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens.
Anna Vidal-Crespo,Alba Matas-Céspedes,Vanina Rodriguez,Cédric Rossi,Juan G. Valero,Neus Serrat,Alejandra Sanjuan-Pla,Pablo Menendez,Gaël Roué,Armando López-Guillermo,Eva Giné,Elias Campo,Dolors Colomer,Christine Bezombes,Jeroen J. Lammerts van Bueren,Christopher Chiu,Parul Doshi,Patricia Pérez-Galán +17 more
TL;DR: Daratumumab constitutes a novel therapeutic opportunity in certain scenarios and these results warrant further clinical development.
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Autologous hematopoietic stem cell transplantation for intravascular large B-cell lymphoma: the European Society for Blood and Marrow Transplantation experience
Julia Meissner,Herve Finel,Sascha Dietrich,Ariane Boumendil,Edward Kanfer,G. Laboure,Manuel Abecasis,Jan J. Cornelissen,Jeremy Delage,Jürgen Finke,Urs Hess,Heinz Ludwig,Mohamad Mohty,Thomas Pabst,Pietro Pioltelli,Stephen D. Robinson,Panagiotis Samaras,Silvia Montoto,Peter Dreger +18 more
TL;DR: Autologous hematopoietic stem cell transplantation for intravascular large B-cell lymphoma: the European Society for Blood and Marrow Transplantation experience is described.
References
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WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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