The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
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TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
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Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas
Daniel Hübschmann,Kortine Kleinheinz,Kortine Kleinheinz,Rabea Wagener,Rabea Wagener,Rabea Wagener,Stephan H. Bernhart,Cristina López,Cristina López,Umut H. Toprak,Umut H. Toprak,Stephanie Sungalee,Naveed Ishaque,Helene Kretzmer,Markus Kreuz,Sebastian M. Waszak,Nagarajan Paramasivam,Nagarajan Paramasivam,Ole Ammerpohl,Ole Ammerpohl,Sietse M. Aukema,Renée Beekman,Anke K. Bergmann,Matthias Bieg,Hans Binder,Arndt Borkhardt,Christoph Borst,Benedikt Brors,Philipp Bruns,Enrique Carrillo de Santa Pau,Alexander Claviez,Gero Doose,Andrea Haake,Dennis Karsch,Siegfried Haas,Martin-Leo Hansmann,Jessica I. Hoell,Volker Hovestadt,Bingding Huang,Michael Hummel,Christina Jäger-Schmidt,Jules Kerssemakers,Jan O. Korbel,Dieter Kube,Chris Lawerenz,Dido Lenze,Joost H.A. Martens,German Ott,Bernhard Radlwimmer,Eva Reisinger,Julia Richter,Daniel Rico,Philip Rosenstiel,Andreas Rosenwald,Markus Schillhabel,Stephan Stilgenbauer,Peter F. Stadler,José I. Martín-Subero,Monika Szczepanowski,Gregor Warsow,Marc A. Weniger,Marc Zapatka,Alfonso Valencia,Hendrik G. Stunnenberg,Peter Lichter,Peter Möller,Markus Loeffler,Roland Eils,Roland Eils,Wolfram Klapper,Steve Hoffmann,Lorenz Trümper,Ralf Küppers,Matthias Schlesner,Matthias Schlesner,Reiner Siebert,Reiner Siebert +76 more
TL;DR: In this paper, the authors performed whole genome and transcriptome sequencing of 181 germinal center derived B-cell lymphomas (gcBCL) and identified distinct mutational signatures linked to SHM and CSR.
Journal ArticleDOI
Genomic subtypes may predict the risk of central nervous system recurrence in diffuse large B-cell lymphoma.
Thomas A Ollila,Thomas A Ollila,Habibe Kurt,Jozal Waroich,Jozal Waroich,John Vatkevich,Ashlee Sturtevant,Nimesh R. Patel,Patrycja M. Dubielecka,Patrycja M. Dubielecka,Diana O. Treaba,Adam J. Olszewski,Adam J. Olszewski +12 more
TL;DR: It is reported that most tumors with CNS recurrence have recognizable molecular features that fall into two categories: those that resemble primary CNS lymphoma andThose that resemble high-grade lymphoma.
Journal ArticleDOI
Clinicopathological analysis of oral diffuse large B‐cell lymphoma, NOS: A systematic review
Carla Isabelly Rodrigues-Fernandes,Lucas Lacerda de Souza,Sara Ferreira Dos Santos-Costa,Hélder Antônio Rebelo Pontes,Oslei Paes de Almeida,Pablo Agustin Vargas,Javier Rendón Henao,Siavash Rahimi,Peter A. Brennan,Felipe Paiva Fonseca,Felipe Paiva Fonseca +10 more
TL;DR: Oral DLBCL NOS is an aggressive malignancy, but with a high survival rate, and its clinicopathological features are described, identifying potential prognostic factors.
Journal ArticleDOI
Canine nodal marginal zone lymphoma: descriptive insight into the biological behaviour.
Marzia Cozzi,Laura Marconato,Valeria Martini,Luca Aresu,Fulvio Riondato,Federica Rossi,Damiano Stefanello,Stefano Comazzi +7 more
TL;DR: The outcome is poor, despite the "indolent" designation for canine nMZL, and the best treatment option still needs to be defined.
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Ultra-Rapid Reporting of GENomic Targets (URGENTseq): Clinical Next-Generation Sequencing Results within 48 Hours of Sample Collection
Keyur P. Patel,Roberto Ruiz-Cordero,Wei Chen,Mark J. Routbort,Kristen Floyd,Sergio Rodriguez,John Galbincea,Bedia A. Barkoh,David Hatfield,Haitham Khogeer,Rashmi Kanagal-Shamanna,C. Cameron Yin,Zhuang Zuo,Sanam Loghavi,Chi Young Ok,Courtney D. DiNardo,Rajyalakshmi Luthra,L. Jeffrey Medeiros +17 more
TL;DR: A novel custom platform designated as Ultra-rapid Reporting of GENomic Targets (URGENTseq), an integrated solution that includes workflow optimization and an innovative custom bioinformatics pipeline to provide targeted NGS results on fresh peripheral blood and bone marrow samples within an actionable time period.
References
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Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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