The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
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TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
Citations
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Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study.
Jeremy S. Abramson,M. Lia Palomba,Leo I. Gordon,Matthew A. Lunning,Michael Wang,Jon E. Arnason,Amitkumar Mehta,Enkhtsetseg Purev,David G. Maloney,Charalambos Andreadis,Alison R. Sehgal,Scott R. Solomon,Nilanjan Ghosh,Tina Albertson,Jacob Garcia,Ana Kostic,Mary Mallaney,Ken Ogasawara,Kathryn Newhall,Yeonhee Kim,Daniel Li,Tanya Siddiqi +21 more
TL;DR: Overall safety and activity of liso-cel did not differ by dose level, with a high objective response rate, and a low incidence of grade 3 or worse cytokine release syndrome and neurological events in patients with relapsed or refractory large B-cell lymphomas.
Journal ArticleDOI
Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis
TL;DR: The cancer burden attributed to human papillomavirus showed the clearest relationship with country income level, and infection-attributable cancer incidence allows for refined geographic analyses and identification of populations with a high infection-associated cancer burden.
Journal ArticleDOI
2016 US lymphoid malignancy statistics by World Health Organization subtypes.
Lauren R. Teras,Carol DeSantis,James R. Cerhan,Lindsay M. Morton,Ahmedin Jemal,Christopher R. Flowers +5 more
TL;DR: Estimates of the total numbers of US lymphoid neoplasm cases by subtype as well as a detailed evaluation of incidence and survival statistics are presented, which can offer clues regarding their etiology.
Journal ArticleDOI
Infection in Organ Transplantation
TL;DR: Transplant infectious disease remains a key to the clinical and scientific investigation of organ transplantation and application of quantitative molecular microbial assays and advanced antimicrobial therapies have advanced care.
Journal ArticleDOI
International Consensus Classification of Myeloid Neoplasms and Acute Leukemia: Integrating Morphological, Clinical, and Genomic Data.
Daniel A. Arber,Attilio Orazi,Robert P. Hasserjian,Michael Horowitz,Katherine R. Calvo,Hans Michael Kvasnicka,Sa A. Wang,Adam Bagg,Tiziano Barbui,Susan Branford,Carlos E. Bueso-Ramos,Jorge E. Cortes,Paola Dal Cin,Courtney D. DiNardo,Hervé Dombret,Eric J. Duncavage,Benjamin L. Ebert,Elihu H. Estey,Fabio Facchetti,Kathryn Foucar,Naseema Gangat,Umberto Gianelli,Lucy A. Godley,Nicola Goekbuget,Jason Gotlib,Eva Hellström-Lindberg,Gabriela S. Hobbs,Roald Hoffmann,Elias Jabbour,Jean-Jacques Kiladjian,Richard A. Larson,Michelle M. Le Beau,Mignon L. Loh,Bob Löwenberg,Elizabeth Macintyre,Luca Malcovati,Charles G. Mullighan,Charlotte M. Niemeyer,Olatoyosi Odenike,Seishi Ogawa,Alberto Orfao,Elli Papaemmanuil,Francesco Passamonti,Kimmo Porkka,C H Pui,Jerald P. Radich,Andreas Reiter,María Rozman,Martina Rudelius,Michael R. Savona,Charles A. Schiffer,Annette Schmitt-Graeff,Akiko Shimamura,Jorge Sierra,Wendy Stock,Richard Stone,Martin S. Tallman,Juergen Thiele,Hwei-Fang Tien,Alexandar Tzankov,Alessandro M. Vannucchi,Paresh Vyas,Andrew H. Wei,Olga Weinberg,Agnieszka Wierzbowska,Mario Cazzola,Hartmut Döhner,Ayalew Tefferi +67 more
TL;DR: The authors, a group with expertise in the clinical, pathologic and genetic aspects of these disorders, developed the International Consensus Classification (ICC), aimed at facilitating diagnosis and prognostication of these neoplasms, improving treatment of affected patients, and allowing the design of innovative clinical trials.
References
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Primary Follicular Lymphoma of the Duodenum Is a Distinct Mucosal/Submucosal Variant of Follicular Lymphoma: A Retrospective Study of 63 Cases
Ana-Iris Schmatz,Berthold Streubel,Elisabeth Kretschmer-Chott,Andreas Püspök,Ulrich Jäger,Christine Mannhalter,Markus Tiemann,German Ott,Wolfgang Fischbach,Peter Herzog,Gerhard Seitz,Manfred Stolte,Markus Raderer,Andreas Chott +13 more
TL;DR: These findings characterize primary FL-D as a remarkably indolent FL variant, which, even left untreated, does not develop tumorous growth, very rarely disseminates and does not transform to high grade disease.
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Breast implant-associated anaplastic large cell lymphoma: two distinct clinicopathological variants with different outcomes
Camille Laurent,Audrey Delas,P. Gaulard,Corinne Haioun,Anne Moreau,Luc Xerri,Alexandra Traverse-Glehen,Thérèse Rousset,Isabelle Quintin-Roue,Tony Petrella,Jean-François Emile,Nadia Amara,Philippe Rochaix,M.P. Chenard-Neu,A.M. Tasei,E. Menet,H. Chomarat,V. Costes,L. Andrac-Meyer,Jean-François Michiels,Catherine Chassagne-Clément,L. de Leval,Pierre Brousset,Georges Delsol,Laurence Lamant +24 more
TL;DR: In situ ALK-negative anaplastic large cell lymphoma associated with breast implant have an indolent clinical course and generally remain free of disease after implant removal, however, infiltrative i-ALCLs could have a more aggressive clinical course that might require additional therapy to implant removal.
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C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma.
Aldo M. Roccaro,Antonio Sacco,Cristina Jimenez,Patricia Maiso,Michele Moschetta,Yuji Mishima,Yosra Aljawai,Ilyas Sahin,Michelle Kuhne,Pina M. Cardarelli,Lewis J. Cohen,Jesús F. San Miguel,Ramón García-Sanz,Irene M. Ghobrial +13 more
TL;DR: It is demonstrated that C1013G/CXCR4 is an activating mutation in WM and support its role as a critical regulator of WM molecular pathogenesis and as an important therapeutic target.
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Hepatosplenic alphabeta T-cell lymphomas: a report of 14 cases and comparison with hepatosplenic gammadelta T-cell lymphomas.
William R. Macon,Norman B. Levy,Paul J. Kurtin,Kevin E. Salhany,Mohamed Y. Elkhalifa,Terence T. Casey,Fiona E. Craig,Cindy L. Vnencak-Jones,Margaret L. Gulley,Jonathan P. Park,John B. Cousar +10 more
TL;DR: Data show that hepatosplenic T-cell lymphomas include an alphabeta-subtype, along with the previously recognized gammadelta group, which should be recognized as phenotypically heterogeneous subtypes of the same disease entity.
Journal ArticleDOI
Primary cutaneous CD4+ small-/medium-sized pleomorphic T-cell lymphoma: a cutaneous nodular proliferation of pleomorphic T lymphocytes of undetermined significance? A study of 136 cases.
TL;DR: The incongruity between the indolent clinical course and the worrying histopathologic and molecular features poses difficulties in classifying cases unambiguously as benign or malignant, and it may be better to refer to them with a descriptive term such as “cutaneous nodular proliferation of pleomorphic T lymphocytes of undetermined significance,” rather than forcing them into one or the other category.
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