The 2016 revision of the World Health Organization classification of lymphoid neoplasms
Steven H. Swerdlow,Elias Campo,Stefano Pileri,Nancy L. Harris,Harald Stein,Reiner Siebert,Ranjana H. Advani,Michele Ghielmini,Gilles Salles,Andrew D. Zelenetz,Elaine S. Jaffe +10 more
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TLDR
The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies.About:
This article is published in Blood.The article was published on 2016-05-19 and is currently open access. It has received 5321 citations till now.read more
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Anaplastic Variant of Diffuse Large B-cell Lymphoma Displays Intricate Genetic Alterations and Distinct Biological Features.
Mingyang Li,Yixiong Liu,Yingmei Wang,Gang Chen,Qiongrong Chen,Hualiang Xiao,Fang Liu,Chubo Qi,Zhou Yu,Xia Li,Linni Fan,Ying Guo,Qingguo Yan,Shuangping Guo,Zhe Wang +14 more
TL;DR: Cases of A-DLBCL more often had a high International Prognostic Index score and a non–germinal center B-cell immunophenotype, more frequently expressed CD30 and p53, and more frequently had mutations of TP53 and concurrent abnormalities of MYC and BCL2 and/or BCL6.
Journal ArticleDOI
Positron emission tomography computed tomography features of monomorphic epitheliotropic intestinal T-cell lymphoma.
TL;DR: Findings showed that in contrast to classical enteropathy-associated T-cell lymphoma, MEITL might on presentation and during relapse involve any part of the gut, and metastasize to multiple extra-intestinal sites.
Journal ArticleDOI
Abdominal involvement in Erdheim-Chester disease (ECD): MRI and CT imaging findings and their association with BRAFV600E mutation.
Moozhan Nikpanah,Lauren Kim,S. Mojdeh Mirmomen,Rolf Symons,Ioannis Papageorgiou,William A. Gahl,Kevin O'Brien,Juvianee Estrada-Veras,Ashkan A. Malayeri +8 more
TL;DR: Renal and vascular structures are the most commonly affected abdominal organs in ECD patients and some of these findings have significant positive association with the BRAFV600E mutation.
Journal ArticleDOI
Breast Implant-associated Anaplastic Large Cell Lymphoma: An Evidence-based Systematic Review.
Ryan C. DeCoster,Evan B. Lynch,Alisha R. Bonaroti,John Matthew Webster,Timothy A. Butterfield,B.M. Evers,Henry C. Vasconez,Mark W. Clemens +7 more
TL;DR: The clinical knowledge of BIA-ALCL has evolved rapidly over the last several years with major advances in diagnosis and treatment, including en bloc resection as the standard of care, and current evidence aligns with established NCCN consensus guidelines.
Journal ArticleDOI
TCR β chain–directed bispecific antibodies for the treatment of T cell cancers
Suman Paul,Alexander H. Pearlman,Jacqueline Douglass,Brian J. Mog,Emily Han-Chung Hsiue,Michael S. Hwang,Sarah R. DiNapoli,Maximilian F. Konig,Patrick A. Brown,Katharine M. Wright,Surojit Sur,Sandra B. Gabelli,Sandra B. Gabelli,Yana Li,Gabriel Ghiaur,Drew M. Pardoll,Nickolas Papadopoulos,Chetan Bettegowda,Kenneth W. Kinzler,Shibin Zhou,Bert Vogelstein +20 more
TL;DR: In this paper, an approach to target T cell cancers through T cell receptor (TCR) antigens was proposed. But, the approach is not suitable for T cell malignancy.
References
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Book
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
TL;DR: Thank you very much for reading who classification of tumours of haematopoietic and lymphoid tissues, and maybe you have knowledge that, people have look hundreds of times for their chosen readings like this, but end up in malicious downloads.
Journal ArticleDOI
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
TL;DR: The criteria and significance of early or precursor lesions and the identification of certain lymphoid neoplasms largely associated with particular age groups, such as children and the elderly are addressed, and the issue of borderline categories having overlapping features with large B-cell lymphomas is reviewed.
Journal ArticleDOI
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Xose S. Puente,Magda Pinyol,Víctor Quesada,Laura Conde,Gonzalo R. Ordóñez,Neus Villamor,Geòrgia Escaramís,Pedro Jares,Sílvia Beà,Marcos González-Díaz,Laia Bassaganyas,Tycho Baumann,Manel Juan,Mónica López-Guerra,Dolors Colomer,Jose M. C. Tubio,Cristina López,Alba Navarro,Cristian Tornador,Marta Aymerich,María Rozman,Jesús M. Hernández,Diana A. Puente,José M.P. Freije,Gloria Velasco,Ana Gutiérrez-Fernández,Dolors Costa,Anna Carrió,Sara Guijarro,Anna Enjuanes,Lluis Hernández,Jordi Yagüe,Pilar Nicolás,Carlos M. Romeo-Casabona,Heinz Himmelbauer,Ester Castillo,Juliane C. Dohm,Silvia de Sanjosé,Miguel A. Piris,Enrique de Alava,Jesús F. San Miguel,Romina Royo,Josep Lluís Gelpí,David Torrents,Modesto Orozco,David G. Pisano,Alfonso Valencia,Roderic Guigó,Mònica Bayés,Simon Heath,Marta Gut,Peter Klatt,John Marshall,Keiran Raine,Lucy Stebbings,P. Andrew Futreal,Michael R. Stratton,Peter J. Campbell,Ivo Gut,Armando López-Guillermo,Xavier Estivill,Emili Montserrat,Carlos López-Otín,Elias Campo +63 more
TL;DR: The patterns of somatic mutation, supported by functional and clinical analyses, strongly indicate that the recurrent NOTCH1, MYD88 and XPO1 mutations are oncogenic changes that contribute to the clinical evolution of the disease.
Journal ArticleDOI
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon,Lian Xu,Guang Yang,Yangsheng Zhou,Xia Liu,Yang Cao,Patricia Sheehy,Robert Manning,Christopher J. Patterson,Christina K. Tripsas,Luca Arcaini,Geraldine S. Pinkus,Scott J. Rodig,Aliyah R. Sohani,Nancy L. Harris,Jason M. Laramie,Donald A Skifter,Stephen E Lincoln,Zachary R. Hunter +18 more
TL;DR: MYD88 L265P is a commonly recurring mutation in patients with Waldenström's macroglobulinemia that can be useful in differentiating WaldenStröm’s macrogalobulinesia and non-IgM LPL from B-cell disorders that have some of the same features.
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