The Scourge of Antibiotic Resistance: The Important Role of the Environment
Rita Finley,Peter Collignon,D. G. Joakim Larsson,Scott A. McEwen,Xian-Zhi Li,William H. Gaze,Richard J. Reid-Smith,Mohammed Timinouni,David W. Graham,Edward Topp +9 more
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The rapid evolution and spread of "new" antibiotic resistance genes has been enhanced by modern human activity and its influence on the environmental resistome, which highlights the importance of including the role of the environmental vectors, such as bacterial genetic diversity within soil and water, in resistance risk management.Abstract:
Antibiotic resistance and associated genes are ubiquitous and ancient, with most genes that encode resistance in human pathogens having originated in bacteria from the natural environment (eg, β-lactamases and fluoroquinolones resistance genes, such as qnr). The rapid evolution and spread of "new" antibiotic resistance genes has been enhanced by modern human activity and its influence on the environmental resistome. This highlights the importance of including the role of the environmental vectors, such as bacterial genetic diversity within soil and water, in resistance risk management. We need to take more steps to decrease the spread of resistance genes in environmental bacteria into human pathogens, to decrease the spread of resistant bacteria to people and animals via foodstuffs, wastes and water, and to minimize the levels of antibiotics and antibiotic-resistant bacteria introduced into the environment. Reducing this risk must include improved management of waste containing antibiotic residues and antibiotic-resistant microorganisms.read more
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Antibiotic Resistance in Wastewater Treatment Plants and Transmission Risks for Employees and Residents: The Concept of the AWARE Study
Laura Wengenroth,Fanny Berglund,Hetty Blaak,Mariana Carmen Chifiriuc,Carl-Fredrik Flach,Gratiela Gradisteanu Pircalabioru,D. G. J. Larsson,Luminita Marutescu,M. van Passel,Marcela Popa,Katja Radon,AM de Roda Husman,Daloha Rodríguez-Molina,Tobias Weinmann,Andreas Wieser,Heike Schmitt +15 more
TL;DR: The AWARE (Antibiotic Resistance in Wastewater: Transmission Risks for Employees and Residents around Waste Water Treatment Plants) study as mentioned in this paper investigates the transmission of antibiotic resistance from wastewater treatment plants to humans, most importantly to WWTP workers and residents living in the vicinity.
Journal ArticleDOI
Quinolone Resistant Enterobacteriaceae and Pseudomonas in Environ-mental Water in Dhaka, Bangladesh
TL;DR: It is suggested that potential role of water for the dissemination and transmission of resistant genes among microorganisms causing human and animal infections in Bangladesh is underestimated.
Journal ArticleDOI
Screening of the Promising Phytogenic Medicinal Materials among the Plant Species of Altai Flora by Supercritical Fluid Extraction
TL;DR: In this paper, supercritical fluid extraction using supercritical carbon dioxide was used to extract antibiotic properties of 34 plant species of Altai flora, including Penthaphylloides fruticosa and Ribes nigrum.
Journal ArticleDOI
Using MALDI-TOF Mass Spectrometry to Identify Drug Resistant Staphylococcal Isolates from Nonhospital Environments in Brunei Darussalam
TL;DR: This work provides the first-ever evidence of drug resistant staphylococci in the nonhospital environment in Brunei Darussalam.
Journal Article
A Review of the Presence of Antibiotic Resistance Problems on Klebsiella Pneumoniae Acquired from Pigs: Public Health Importance
Eka Dian Sofiana,Junianto Wika Adi Pratama,Mustofa Helmi Effendi,Hani Plumeriastuti,Freshindy Marissa Wibisono,Erwan Budi Hartadi,Akvyan Rafi Hidayatullah +6 more
TL;DR: In this paper, the authors summarized several strains, resistant antibiotics, antibiotic resistance genes and virulence genes of the Klebsiella pneumoniae bacteria in pigs which were summarized in this article.
References
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Antibiotics and antibiotic resistance in water environments
TL;DR: Methods to reduce resistant bacterial load in wastewaters, and the amount of antimicrobial agents, in most cases originated in hospitals and farms, include optimization of disinfection procedures and management of wastewater and manure.