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Institution

Jewish Hospital

HealthcareCincinnati, Ohio, United States
About: Jewish Hospital is a healthcare organization based out in Cincinnati, Ohio, United States. It is known for research contribution in the topics: Antigen & Population. The organization has 3881 authors who have published 3414 publications receiving 123044 citations.


Papers
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Journal ArticleDOI
TL;DR: Metformin-diet before and during pregnancy in PCOS reduces miscarriage and adverse pregnancy outcomes and individual benefits of the diet alone and diet plus metformin could be assessed separately.
Abstract: Objective:Prospectively assess whether metformin/diet pre-conception and throughout pregnancy would safely reduce first trimester miscarriage and improve pregnancy outcomes in women with polycystic ovary syndrome (PCOS).Research design and methods:In 76 PCOS women, first pregnancy miscarriage and live birth were compared before and on metformin/diet, started 6.8 months (median) before conception, continued throughout pregnancy. On metformin 2–2.55 g/day, low glycemic index diet, first pregnancy outcomes in PCOS were compared with 156 community obstetric practice women (controls).Main outcome measures:Live births, miscarriage, birth <37 weeks gestation, gestational diabetes, pre-eclampsia, fetal macrosomia.Results:In 76 PCOS women before metformin-diet, there were 36 miscarriages (47%) and 40 live births vs. 14 (18%) miscarriages and 62 live births on metformin-diet 6.8 months before conception and throughout pregnancy, p = 0.0004, OR 3.99, 95% CI 1.91–8.31. On metformin-diet, PCOS women did not di...

33 citations

Journal ArticleDOI
TL;DR: The synthesis of the adenylate cyclase of Escherichia coli, appears to be regulated negatively by the cAMP receptor protein CRP, based on a comparison of adenYLate cycl enzyme activities measured in vitro with the rates of cAMP synthesis by intact bacteria.
Abstract: The synthesis of the adenylate cyclase [ATP pyrophosphatelyase-(cyclizing), E.C. 4.6.1.1.] of Escherichia coli, appears to be regulated negatively by the cAMP receptor protein CRP. This conclusion is based on a comparison of adenylate cyclase activities measured in vitro with the rates of cAMP synthesis by intact bacteria. The activity of adenylate cyclase, depending on conditions of growth, is also regulated by CRP; this effect, however, is indirect insofar as it is mediated by a protein or proteins under CRP control.

33 citations

Journal ArticleDOI
TL;DR: Reduction of the arterial elastance with intra-aortic balloon pumping improved the ventriculoarterial coupling ratio and increased stroke volume, which suggests the conservation of the myocardial oxygen consumption.

33 citations


Authors

Showing all 3894 results

NameH-indexPapersCitations
John C. Morris1831441168413
David L. Kaplan1771944146082
Robert H. Purcell13966670366
Nancy J. Cox135778109195
Jennifer S. Haas12884071315
David A. Cheresh12533762252
John W. Kappler12246457541
Philippa Marrack12041654345
Arthur Weiss11738045703
Thomas J. Kipps11474863240
Michael Pollak11466357793
Peter M. Henson11236954246
Roberto Bolli11152844010
William D. Foulkes10868245013
David A. Lynch10871459678
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20232
202217
202148
202039
201944
201828