Jewish Hospital

About: Jewish Hospital is a healthcare organization based out in Cincinnati, Ohio, United States. It is known for research contribution in the topics: Antigen & Population. The organization has 3881 authors who have published 3414 publications receiving 123044 citations.

Primary structural relationship of p16 to m16 ribosomal RNA.

Abstract: IMMATURE ribosomes contain RNAs which can be distinguished from the molecules present in mature ribosomes1. The precursor of 16S rRNA (p16) can be identified in pulse labelled cells2–4; the conversion of p16 to mature 16S rRNA (m16) occurs during the latter stages of ribosome assembly and demands concomitant protein synthesis1. We have compared oligonucleotide fingerprints of E. coli p16 and m16 rRNA mixtures, labelled respectively with32P and3H or32P and33P and now report that the precursor is of 10% greater molecular weight than the mature molecules. Identifiable sequences are cleaved from the precursor during the maturation process.

Analysis of behavioral traits in the presence of cultural transmission and assortative mating: Applications to IQ and SES.

Abstract: General linear models of familial resemblance are described which allow for polygenic inheritance, cultural transmission from parent to offspring, phenotypic assortative mating, common environment, and maternal and parental effects. These models use observed phenotypic correlations between multiple classes of relatives and/or correlations between individuals reared in separated and extended family structures to yield maximum likelihood parameter estimates. The models are first applied to American kinship data for IQ, with the variance of IQ partitioned as 30% additive genetic, 29% due to cultural inheritance, 9% due to gene--culture covariance, and 32% due to nontransmissible environment. Under the assumption that the correlations between (nontransmissible) environments of DZ and MZ twins are the same, an approximate treatment of dominance yields an estimate of 23% dominance variation.

HEREDITY OF THE Rh BLOOD TYPES

Abstract: IN previous papers of this series,1, 2, 3, 4, 5, 6 studies were described on the heredity of the Rh—Hr blood types in a series of 525 families with 925 children. The results of these family studies, as well as the statistical analysis of the distributions of the Rh—Hr type in various populations throughout the world have confirmed the accuracy of the theory of heredity of the Rh—Hr blood types by multiple allelic genes.