Manipal University

About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Medicine. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.

Potential of Natural Fibers in Composites for Ballistic Applications – A Review

Abstract: In this paper, a review of natural fibers composites used in protective armors for ballistic applications like bulletproof vests is presented. It seeks to compile the results and establish natural ...

Biogenic synthesis of ferric oxide nanoparticles using the leaf extract of Peltophorum pterocarpum and their catalytic dye degradation potential

Abstract: Plant-mediated green synthesis of nanoparticles is an eco-friendly and cheap method since it makes use of phyto-compounds present in various plant parts as reducing and stabilizing agents. Herein, magnetic, ferric oxide nanoparticles (FONPs) were prepared by utilizing the leaf extract of Peltophorum pterocarpum for the first time. Rod-like FONPs with agglomerations were witnessed in FE-SEM images. Sharp peaks for elemental oxygen and iron were witnessed in EDS spectrum. XRD spectrum ascertained the crystallinity of the FONPs and showed both γ and α–Fe 2 O 3 phases. The average crystallite size was 16.99 nm. A large specific surface area (66.44 m 2 /g) was found in BET analysis and the FONPs were mesoporous (pore diameter = 7.92 nm). TGA results showed a 20% weight loss during heating up to 800 °C. FTIR spectrum showed significant bands for various phyto-compounds and Fe–O. The Fenton-like catalytic efficiency of FONPs was studied for the methylene blue dye degradation during which 90% removal was noticed within 220min. The experimental results were satisfactorily fitted into a second-order model with a degradation constant of 0.0987 L/mg min. Also, the catalytic activity of the FONPs was assessed for the removal of MB dye with the reducing agent NaBH 4 . A remarkable dye degradation (92%) was attained within 27min, and the results were best suited for a first-order model with a kinetic degradation constant of 0.0856min −1 . Therefore, the green-synthesized FONPs obtained here could be used in the degradation of dyes as nanocatalysts for the remediation of wastewater.

A network map of Interleukin-10 signaling pathway.

Abstract: Interleukin-10 (IL-10) is an anti-inflammatory cytokine with important immunoregulatory functions It is primarily secreted by antigen-presenting cells such as activated T-cells, monocytes, B-cells and macrophages In biologically functional form, it exists as a homodimer that binds to tetrameric heterodimer IL-10 receptor and induces downstream signaling IL-10 is associated with survival, proliferation and anti-apoptotic activities of various cancers such as Burkitt lymphoma, non-Hodgkins lymphoma and non-small scell lung cancer In addition, it plays a central role in survival and persistence of intracellular pathogens such as Leishmania donovani, Mycobacterium tuberculosis and Trypanosoma cruzi inside the host The signaling mechanisms of IL-10 cytokine are not well explored and a well annotated pathway map has been lacking To this end, we developed a pathway resource by manually annotating the IL-10 induced signaling molecules derived from literature The reactions were categorized under molecular associations, activation/inhibition, catalysis, transport and gene regulation In all, 37 molecules and 76 reactions were annotated The IL-10 signaling pathway can be freely accessed through NetPath, a resource of signal transduction pathways previously developed by our group