Manipal University

About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Medicine. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.

Impact of technostress on academic productivity of university students

Abstract: There has been increasing interest among researchers to understand the negative effects of technology, in the last two decades. Technostress or stress induced due to technology is extensively reported in the literature, among working professionals. Even though there has been an increased proliferation of digital devices in academia, there is a dearth of studies examining the prevalence of technostress and its impact among students. This study examines the prevalence of technostress among the younger population, in the age group of 18–28 years. Using a sample of 673 Indian private university students, this study cross-validated the technostress instrument. Increased use of technology in higher education has compelled students to complete all their academic work, including assessments, using technology. Technology-enhanced learning applications such as learning management systems, MOOCs and digital exam devices require students to develop ICT skills. The study also investigates the impact of technostress on the academic productivity of students. Findings reveal that the technostress instrument is valid to be used in the academic context, with minor modifications, and students experienced moderate levels of technostress. It was also found that technostress had a negative impact on the academic productivity of students.

Fast Transport of Water Droplets over a Thermo-Switchable Surface Using Rewritable Wettability Gradient.

Abstract: In spite of the reported temperature dependent tunability in wettability of poly(N-isopropylacrylamide) (PNIPAAm) surfaces for below and above lower critical solution temperature (32 °C), the transport of water droplets is inhibited by the large contact angle hysteresis. Herein, for the first time, we report on-demand, fast, and reconfigurable droplet manipulation over a PNIPAAm grafted structured polymer surface using temperature-induced wettability gradient. Our study reveals that the PNIPAAm grafted on intrinsically superhydrophobic surfaces exhibit hydrophilic nature with high contact angle hysteresis below 30 °C and superhydrophobic nature with ultralow contact angle hysteresis above 36 °C. The transition region between 30 and 36 °C is characterized by a large change in water contact angle (∼100°) with a concomitant change in contact angle hysteresis. By utilizing this “transport zone” wherein driving forces overcome the frictional forces, we demonstrate macroscopic transport of water drops with a ma...

Dental pulp stem cells immobilized in alginate microspheres for applications in bone tissue engineering

Abstract: Aim To immobilize dental pulp stem cells (DPSC) in alginate microspheres and to determine cell viability, proliferation, stem cell characteristics and osteogenic potential of the immobilized DPSCs. Methodology Human DPSCs isolated from the dental pulp were immobilized in 1% w/v alginate microspheres. Viability and proliferation of immobilized DPSCs were determined by trypan blue and MTT assay, respectively. Stem cell characteristics of DPSCs post immobilization were verified by labelling the cells with CD73 and CD90. Osteogenic potential of immobilized DPSCs was assessed by the presence of osteocalcin. Alizarin red staining and O-cresolphthalein complexone method confirmed and quantified calcium deposition. A final reverse transcriptase PCR evaluated the expression of osteogenic markers – ALP, Runx-2 and OCN. Results More than 80% of immobilized DPSCs were viable throughout the 3-week study. Proliferation appeared controlled and consistent unlike DPSCs in the control group. Presence of CD73 and CD90 markers confirmed the stem cell nature of immobilized DPSCs. The presence of osteocalcin, an osteoblastic marker, was confirmed in the microspheres on day 21. Mineralization assays showed high calcium deposition indicating elevated osteogenic potential of immobilized DPSCs. Osteogenic genes- ALP, Runx-2 and OCN were also upregulated in immobilized DPSCs. Surprisingly, immobilized DPSCs in the control group cultured in conventional stem cell media showed upregulation of osteogenic genes and expressed osteocalcin. Conclusion Dental pulp stem cells immobilized in alginate hydrogels exhibit enhanced osteogenic potential while maintaining high cell viability both of which are fundamental for bone tissue regeneration.