Nankai University

About: Nankai University is a education organization based out in Tianjin, China. It is known for research contribution in the topics: Catalysis & Adsorption. The organization has 42964 authors who have published 51866 publications receiving 1127896 citations. The organization is also known as: Nánkāi Dàxué.

Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure.

Abstract: Immunogenic cell death (ICD) provides momentous theoretical principle for modern cancer immunotherapy. However, the currently available ICD inducers are still very limited and photosensitizer-based ones can hardly induce sufficient ICD to achieve satisfactory cancer immunotherapy by themselves. Herein, an organic photosensitizer (named TPE-DPA-TCyP) with a twisted molecular structure, strong aggregation-induced emission activity, and specific ability is reported for effectively inducing focused mitochondrial oxidative stress of cancer cells, which can serve as a much superior ICD inducer to the popularly used ones, including chlorin e6 (Ce6), pheophorbide A, and oxaliplatin. Furthermore, more effective in vivo ICD immunogenicity of TPE-DPA-TCyP than Ce6 is also demonstrated using a prophylactic tumor vaccination model. The underlying mechanism of the effectiveness and robustness of TPE-DPA-TCyP in inducing antitumor immunity and immune-memory effect in vivo is verified by immune cell analyses. This study thus reveals that inducing focused mitochondrial oxidative stress is a highly effective strategy to evoke abundant and large-scale ICD.

Function-oriented design of conjugated carbonyl compound electrodes for high energy lithium batteries

Abstract: Organic carbonyl compounds are potentially low-cost, sustainable, and high energy density electrode materials, but are plagued by unsatisfactory active-site utilization, low discharge potentials and low rate discharge–charge performance in battery applications. We herein disclose a function-oriented design of carbonyl compounds with multi-electron reactions as positive electrode materials for rechargeable lithium batteries, showing that molecular orbital profiles and energetics can be applied for the prediction of carbonyl utilization and modulation of redox potentials. By embedding pre-aromatic 1,2-dicarbonyl moieties in the extended conjugated systems, the desirable molecules integrate all known stabilizing factors and enable full four-Li uptake. Remarkably, two new carbonyl electrodes, pyrene-4,5,9,10-tetraone and 1,10-phenanthroline-5,6-dione, deliver a reversible capacity of 360 mA h g−1 and an average working potential of 2.74 V, respectively, providing insights in designing high-energy organic positive electrodes of lithium batteries for efficient energy storage and conversion.

MnFe2O4@C Nanofibers as High-Performance Anode for Sodium-Ion Batteries.

Abstract: MnFe2O4 nanodots (∼3.3 nm) homogeneously dispersed in porous nitrogen-doped carbon nanofibers (denoted as MFO@C) were prepared by a feasible electrospinning technique. Meanwhile, MFO@C with the character of flexible free-standing membrane was directly used as binder- and current collector-free anode for sodium-ion batteries, exhibiting high electrochemical performance with high-rate capability (305 mA h g–1 at 10000 mA g–1 in comparison of 504 mA h g–1 at 100 mA g–1) and ultralong cycling life (ca. 90% capacity retention after 4200 cycles). The Na-storage mechanism was systematically studied, revealing that MnFe2O4 is converted into metallic Mn and Fe after the first discharge (MnFe2O4 + 8Na+ + 8e– → Mn + 2Fe + 4Na2O) and then to MnO and Fe2O3 during the following charge (Mn + 2Fe + 4Na2O → MnO + Fe2O3 + 8Na+ + 8e–). The subsequent cycles occur through reversible redox reactions of MnO + Fe2O3 + 8Na+ + 8e– ↔ Mn + 2Fe + 4Na2O, of which the reduction/oxidation of MnO/Mn takes place at a lower potential than...

Organic Li4C8H2O6 Nanosheets for Lithium-Ion Batteries

Abstract: Organic tetralithium salts of 2,5-dihydroxyterephthalic acid (Li4C8H2O6) with the morphologies of bulk, nanoparticles, and nanosheets have been investigated as the active materials of either positive or negative electrode of rechargeable lithium-ion batteries. It is demonstrated that, in the electrolyte of LiPF6 dissolved in ethylene carbonate (EC) and dimethyl carbonate (DMC), reversible two-Li-ion electrochemical reactions are taking place with redox Li4C8H2O6/Li2C8H2O6 at ∼2.6 V for a positive electrode and Li4C8H2O6/Li6C8H2O6 at ∼0.8 V for a negative electrode, respectively. In the observed system, the electrochemical performance of high to low order is nanosheets > nanoparticles > bulk. Remarkably, Li4C8H2O6 nanosheets show the discharge capacities of 223 and 145 mAh g–1 at 0.1 and 5 C rates, respectively. A capacity retention of 95% is sustained after 50 cycles at 0.1 C rate charge/discharge and room temperature. Moreover, charging the symmetrical cells with Li4C8H2O6 nanosheets as the initial activ...