University of Alabama

About: University of Alabama is a education organization based out in Tuscaloosa, Alabama, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 27323 authors who have published 48609 publications receiving 1565337 citations. The organization is also known as: Alabama & Bama.

Constraints on the spin-parity and anomalous HVV couplings of the Higgs boson in proton collisions at 7 and 8 TeV

Abstract: The study of the spin-parity and tensor structure of the interactions of the recently discovered Higgs boson is performed using the H to ZZ, Z gamma*, gamma* gamma* to 4 l, H to WW to l nu l nu, and H to gamma gamma decay modes. The full dataset recorded by the CMS experiment during the LHC Run 1 is used, corresponding to an integrated luminosity of up to 5.1 inverse femtobarns at a center-of-mass energy of 7 TeV and up to 19.7 inverse femtobarns at 8 TeV. A wide range of spin-two models is excluded at a 99% confidence level or higher, or at a 99.87% confidence level for the minimal gravity-like couplings, regardless of whether assumptions are made on the production mechanism. Any mixed-parity spin-one state is excluded in the ZZ and WW modes at a greater than 99.999% confidence level. Under the hypothesis that the resonance is a spin-zero boson, the tensor structure of the interactions of the Higgs boson with two vector bosons ZZ, Z gamma, gamma gamma, and WW is investigated and limits on eleven anomalous contributions are set. Tighter constraints on anomalous HVV interactions are obtained by combining the HZZ and HWW measurements. All observations are consistent with the expectations for the standard model Higgs boson with the quantum numbers J[PC]=0[++].

Benefit of interferon β-1a on MSFC progression in secondary progressive MS

Abstract: Background: Interferon β-1a (IFNβ-1a, Avonex) is efficacious in relapsing forms of MS. Studies of other IFNβ preparations in secondary progressive MS (SPMS) yielded conflicting results. This study was undertaken to determine whether IFNβ-1a slowed disease progression in SP-MS. Methods: A total of 436 subjects with SPMS and Expanded Disability Status Scale (EDSS) score 3.5 to 6.5 were randomized to receive IFNβ-1a (60 μg) or placebo by weekly intramuscular injection for 2 years. The primary outcome measure, used for the first time in a large-scale MS trial, was baseline to month 24 change in the MS Functional Composite (MSFC), comprising quantitative tests of ambulation (Timed 25-Foot Walk), arm function (Nine-Hole Peg Test [9HPT]), and cognition (Paced Auditory Serial Addition Test [PASAT]). Results: Median MSFC Z-score change was reduced 40.4% in IFNβ-1a subjects (−0.096 vs −0.161 in placebo subjects, p = 0.033), an effect driven mainly by the 9HPT and PASAT. There was no discernible benefit on the EDSS, which in this range principally reflects walking ability. IFNβ-1a subjects had 33% fewer relapses ( p = 0.008). There was significant benefit on eight of 11 MS Quality of Life Inventory subscales. New or enlarging T2-hyperintense brain MRI lesions and gadolinium-enhancing lesions were reduced at months 12 and 24 (both p Conclusions: IFNβ-1a demonstrated benefit on MSFC progression, relapses, quality of life, and MRI activity in SPMS.

Domestic versus transnational terrorism: Data, decomposition, and dynamics

Abstract: This article devises a method to separate the Global Terrorism Database (GTD) into transnational and domestic terrorist incidents. This decomposition is essential for the understanding of some terrorism phenomena when the two types of terrorism are hypothesized to have different impacts. For example, transnational terrorism may have a greater adverse effect than domestic terrorism on economic growth. Moreover, the causes of the two types of terrorism may differ. Once the data are separated, we apply a calibration method to address some issues with GTD data - namely, the missing data for 1993 and different coding procedures used before 1998. In particular, we calibrate the GTD transnational terrorist incidents to ITERATE transnational terrorist incidents to address GTD's undercounting of incidents in much of the 1970s and its overcounting of incidents in much of the 1990s. Given our assumption that analogous errors characterize domestic terrorist events in GTD, we apply the same calibrations to adjust GTD domestic incidents. The second part of the article investigates the dynamic aspects of GTD domestic and transnational terrorist incidents, based on the calibrated data. Contemporaneous and lagged cross-correlations for the two types of terrorist incidents are computed for component time series involving casualties, deaths, assassinations, bombings, and armed attacks. We find a large cross-correlation between domestic and transnational terrorist incidents that persists over a number of periods. A key finding is that shocks to domestic terrorism result in persistent effects on transnational terrorism; however, the reverse is not true. This finding suggests that domestic terrorism can spill over to transnational terrorism, so that prime-target countries cannot ignore domestic terrorism abroad and may need to assist in curbing this homegrown terrorism.

Exploring an Inverted U-Shape Relationship between Entrepreneurial Orientation and Performance in Chinese Ventures

Abstract: The critical role of entrepreneurial orientation (EO) in firm performance has been widely studied in the U.S. context. However, the examination of this key construct in emerging regions such as Chi...