University of Alabama

About: University of Alabama is a education organization based out in Tuscaloosa, Alabama, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 27323 authors who have published 48609 publications receiving 1565337 citations. The organization is also known as: Alabama & Bama.

Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.

Abstract: background Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain. methods We conducted a randomized trial of hypothermia in infants with a gestational age of at least 36 weeks who were admitted to the hospital at or before six hours of age with either severe acidosis or perinatal complications and resuscitation at birth and who had moderate or severe encephalopathy. Infants were randomly assigned to usual care (control group) or whole-body cooling to an esophageal temperature of 33.5°C for 72 hours, followed by slow rewarming (hypothermia group). Neurodevelopmental outcome was assessed at 18 to 22 months of age. The primary outcome was a combined end point of death or moderate or severe disability. results Of 239 eligible infants, 102 were assigned to the hypothermia group and 106 to the control group. Adverse events were similar in the two groups during the 72 hours of cooling. Primary outcome data were available for 205 infants. Death or moderate or severe disability occurred in 45 of 102 infants (44 percent) in the hypothermia group and 64 of 103 infants (62 percent) in the control group (risk ratio, 0.72; 95 percent confidence interval, 0.54 to 0.95; P=0.01). Twenty-four infants (24 percent) in the hypothermia group and 38 (37 percent) in the control group died (risk ratio, 0.68; 95 percent confidence interval, 0.44 to 1.05; P=0.08). There was no increase in major disability among survivors; the rate of cerebral palsy was 15 of 77 (19 percent) in the hypothermia group as compared with 19 of 64 (30 percent) in the control group (risk ratio, 0.68; 95 percent confidence interval, 0.38 to 1.22; P=0.20). conclusions Whole-body hypothermia reduces the risk of death or disability in infants with moderate or severe hypoxic–ischemic encephalopathy.

BATSE observations of gamma-ray burst spectra. I: Spectral diversity

Abstract: We studied the time-averaged gamma-ray burst spectra accumulated by the spectroscopy detectors of the Burst and Transient Source Experiment. The spectra are described well at low energy by a power-law continuum with an exponential cutoff and by a steeper power law at high energy. However, the spectral parameters vary from burst to burst with no universal values. The break in the spectrum ranges from below 100 keV to more than 1 MeV, but peaks below 200 keV with only a small fraction of the spectra breaking above 400 keV; it is therefore unlikely that a majority of the burst spectra are shaped directly by pair processes, unless bursts originate from a broad redshift range. The correlations among burst parameters do not fulfill the predictions of the cosmological models of burst origin. No correlations with burst morphology or the spatial distribution were found. We demonstrate the importance of using a complete spectral description even if a partial description (e.g., a model without a high-energy tail) is statistically satisfactory.

Modules for experiments in stellar astrophysics (mesa): binaries, pulsations, and explosions

Abstract: We substantially update the capabilities of the open-source software instrument Modules for Experiments in Stellar Astrophysics (MESA). MESA can now simultaneously evolve an interacting pair of differentially rotating stars undergoing transfer and loss of mass and angular momentum, greatly enhancing the prior ability to model binary evolution. New MESA capabilities in fully coupled calculation of nuclear networks with hundreds of isotopes now allow MESA to accurately simulate advanced burning stages needed to construct supernova progenitor models. Implicit hydrodynamics with shocks can now be treated with MESA, enabling modeling of the entire massive star lifecycle, from pre-main sequence evolution to the onset of core collapse and nucleosynthesis from the resulting explosion. Coupling of the GYRE non-adiabatic pulsation instrument with MESA allows for new explorations of the instability strips for massive stars while also accelerating the astrophysical use of asteroseismology data. We improve treatment of mass accretion, giving more accurate and robust near-surface profiles. A new MESA capability to calculate weak reaction rates "on-the-fly" from input nuclear data allows better simulation of accretion induced collapse of massive white dwarfs and the fate of some massive stars. We discuss the ongoing challenge of chemical diffusion in the strongly coupled plasma regime, and exhibit improvements in MESA that now allow for the simulation of radiative levitation of heavy elements in hot stars. We close by noting that the MESA software infrastructure provides bit-for-bit consistency for all results across all the supported platforms, a profound enabling capability for accelerating MESA's development.

First results from KamLAND: evidence for reactor antineutrino disappearance.

Abstract: KamLAND has measured the flux of ν _e’s from distant nuclear reactors. We find fewer ν _e events than expected from standard assumptions about ν _e propagation at the 99.95% C.L. In a 162 ton·yr exposure the ratio of the observed inverse β-decay events to the expected number without ν _e disappearance is 0.611±0.085(stat)±0.041(syst) for ν _e energies >3.4 MeV. In the context of two-flavor neutrino oscillations with CPT invariance, all solutions to the solar neutrino problem except for the “large mixing angle” region are excluded.