Institution
University of Duisburg-Essen
Education•Essen, Nordrhein-Westfalen, Germany•
About: University of Duisburg-Essen is a education organization based out in Essen, Nordrhein-Westfalen, Germany. It is known for research contribution in the topics: Population & Transplantation. The organization has 16072 authors who have published 39972 publications receiving 1109199 citations.
Papers published on a yearly basis
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Dresden University of Technology1, University College London2, Eskişehir Osmangazi University3, Virginia Commonwealth University4, University of Cologne5, Université du Québec à Trois-Rivières6, University of Jena7, University College of Medical Sciences8, Massachusetts Eye and Ear Infirmary9, Konkuk University10, St. Lawrence University11, Cairo University12, Mie University13, Aristotle University of Thessaloniki14, University of Bern15, University of Vermont Medical Center16, University of Insubria17, Kanazawa Medical University18, University of Barcelona19, Medical University of Vienna20, University of Padua21, The Catholic University of America22, University of East Anglia23, University of Chicago24, University of Colorado Boulder25, Université catholique de Louvain26, Wolfson Medical Center27, Taipei Veterans General Hospital28, University of Buenos Aires29, Karolinska University Hospital30, University of Duisburg-Essen31, University of Pardubice32, University Hospital of Basel33
TL;DR: Clinicians and researchers are encouraged to adopt a common language in olfactory dysfunction to increase the methodological quality, consistency and generalisability of work in this field.
Abstract: Background: Olfactory dysfunction is an increasingly recognised condition, associated with reduced quality of life and major health outcomes such as neurodegeneration and death. However, translational research in this field is limited by heterogeneity in methodological approach, including definitions of impairment, improvement and appropriate assessment techniques. Accordingly, effective treatments are limited. In an effort to encourage high quality and comparable work in this field, among others, we propose the following ideas and recommendations. Whilst full recommendations are outlined in the main document, key points include: -Patients with suspected olfactory loss should undergo a full examination of the head and neck, including rigid nasal endoscopy. -Subjective olfactory assessment should not be undertaken in isolation, given its poor reliability. -Psychophysical assessment tools used in clinical and research settings should include reliable and validated tests of odour threshold, and/or one of odour identification or discrimination. -Comprehensive chemosensory assessment should include gustatory screening. -Smell training can be helpful in patients with olfactory loss of several aetiologies. Conclusions: We hope the current manuscript will encourage clinicians and researchers to adopt a common language, and in so doing, increase the methodological quality, consistency and generalisability of work in this field.
473 citations
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Broad Institute1, Harvard University2, Oslo University Hospital3, University of Oslo4, University of Helsinki5, University of Tartu6, Boston Children's Hospital7, Illumina8, Brigham and Women's Hospital9, Charité10, deCODE genetics11, Medical Research Council12, VU University Amsterdam13, Leiden University14, Helsinki University Central Hospital15, Ludwig Maximilian University of Munich16, University of Tübingen17, Karolinska Institutet18, QIMR Berghofer Medical Research Institute19, University of Ulm20, University of Oulu21, King's College London22, Erasmus University Medical Center23, University of Tampere24, University of Duisburg-Essen25, Washington University in St. Louis26, University Medical Center Groningen27, Wellcome Trust Sanger Institute28, University of Oxford29, John Radcliffe Hospital30, Max Planck Society31, University of Kiel32, Technische Universität München33, National Institutes of Health34, Norwegian Institute of Public Health35, University of Copenhagen36, Lundbeck37, Mental Health Services38, Turku University Hospital39, University of Turku40, University of Hamburg41, St George's, University of London42, University of Iceland43, Queensland University of Technology44
TL;DR: For example, the authors identified 44 independent single-nucleotide polymorphisms (SNPs) significantly associated with migraine risk (P < 5 × 10−8) that mapped to 38 distinct genomic loci, including 28 loci not previously reported and a locus that to date is the first to be identified on chromosome X.
Abstract: Migraine is a debilitating neurological disorder affecting around one in seven people worldwide, but its molecular mechanisms remain poorly understood. There is some debate about whether migraine is a disease of vascular dysfunction or a result of neuronal dysfunction with secondary vascular changes. Genome-wide association (GWA) studies have thus far identified 13 independent loci associated with migraine. To identify new susceptibility loci, we carried out a genetic study of migraine on 59,674 affected subjects and 316,078 controls from 22 GWA studies. We identified 44 independent single-nucleotide polymorphisms (SNPs) significantly associated with migraine risk (P < 5 × 10−8) that mapped to 38 distinct genomic loci, including 28 loci not previously reported and a locus that to our knowledge is the first to be identified on chromosome X. In subsequent computational analyses, the identified loci showed enrichment for genes expressed in vascular and smooth muscle tissues, consistent with a predominant theory of migraine that highlights vascular etiologies.
471 citations
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MedStar Washington Hospital Center1, Hebron University2, University of Texas Southwestern Medical Center3, University of Padua4, Cleveland Clinic5, Mayo Clinic6, University of Zurich7, Cornell University8, University of Duisburg-Essen9, Harvard University10, Houston Methodist Hospital11, University of Rostock12, Johns Hopkins University School of Medicine13, University of Michigan14, Yale University15
TL;DR: The aim of this work is to provide a common language for future generations to communicate effectively and effectively with one another about the importance of human rights and democracy.
Abstract: Steven A. Goldstein, MD, Co-Chair, Arturo Evangelista, MD, FESC, Co-Chair, Suhny Abbara, MD, Andrew Arai, MD, Federico M. Asch, MD, FASE, Luigi P. Badano, MD, PhD, FESC, Michael A. Bolen, MD, Heidi M. Connolly, MD, Hug Cu ellar-Cal abria, MD, Martin Czerny, MD, Richard B. Devereux, MD, Raimund A. Erbel, MD, FASE, FESC, Rossella Fattori, MD, Eric M. Isselbacher, MD, Joseph M. Lindsay, MD, Marti McCulloch, MBA, RDCS, FASE, Hector I. Michelena, MD, FASE, Christoph A. Nienaber, MD, FESC, Jae K. Oh, MD, FASE, Mauro Pepi, MD, FESC, Allen J. Taylor, MD, Jonathan W. Weinsaft, MD, Jose Luis Zamorano, MD, FESC, FASE, Contributing Editors: Harry Dietz, MD, Kim Eagle, MD, John Elefteriades, MD, Guillaume Jondeau, MD, PhD, FESC, Herv e Rousseau, MD, PhD, and Marc Schepens, MD, Washington, District of Columbia; Barcelona and Madrid, Spain; Dallas and Houston, Texas; Bethesda and Baltimore, Maryland; Padua, Pesaro, and Milan, Italy; Cleveland, Ohio; Rochester, Minnesota; Zurich, Switzerland; New York, New York; Essen and Rostock, Germany; Boston, Massachusetts; Ann Arbor, Michigan; New Haven, Connecticut; Paris and Toulouse, France; and Brugge, Belgium
470 citations
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TL;DR: In this article, stable Pt electrodes with a spacing down to 4 nm have been fabricated and a new deposition technique, electrostatic trapping, which can be used to bridge the electrodes in a controlled way with a single conducting nanoparticle such as a conjugated or metal cluster molecule.
Abstract: For molecular electronics, one needs the ability to electrically address a single conducting molecule. We report on the fabrication of stable Pt electrodes with a spacing down to 4 nm and demonstrate a new deposition technique, i.e., electrostatic trapping, which can be used to bridge the electrodes in a controlled way with a single conducting nanoparticle such as a conjugated or metal–cluster molecule. In electrostatic trapping, nanoparticles are polarized by an applied electric field and are attracted to the gap between the electrodes where the field is maximum. The feasibility of electrostatic trapping is demonstrated for Pd colloids. Transport measurements on a single Pd nanoparticle show single electron tunneling coexisting with tunnel-barrier suppression.
469 citations
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TL;DR: The main objective of the European Union (EU) funded project AQEM1 was to develop a framework of an assessment system for streams in Europe based on benthic macroinvertebrates that fulfils the requirements of the EU Water Framework Directive.
Abstract: The main objective of the European Union (EU) funded project AQEM1 was to develop a framework of an assessment system for streams in Europe based on benthic macroinvertebrates that fulfils the requirements of the EU Water Framework Directive. Initial assessment methods for 28 European stream types and more generally applicable tools for stream biomonitoring in Europe were generated.
467 citations
Authors
Showing all 16364 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rui Zhang | 151 | 2625 | 107917 |
Olli T. Raitakari | 142 | 1232 | 103487 |
Anders Hamsten | 139 | 611 | 88144 |
Robert Huber | 139 | 671 | 73557 |
Christopher T. Walsh | 139 | 819 | 74314 |
Patrick D. McGorry | 137 | 1097 | 72092 |
Stanley Nattel | 132 | 778 | 65700 |
Luis M. Liz-Marzán | 132 | 616 | 61684 |
Dirk Schadendorf | 127 | 1017 | 105777 |
William Wijns | 127 | 752 | 95517 |
Raimund Erbel | 125 | 1364 | 74179 |
Khalil Amine | 118 | 652 | 50111 |
Hans-Christoph Diener | 118 | 1025 | 91710 |
Bruce A.J. Ponder | 116 | 403 | 54796 |
Andre Franke | 115 | 682 | 55481 |