Journal ArticleDOI
A Meta-Analysis of Cytokines in Alzheimer's Disease
Walter Swardfager,Krista L. Lanctôt,Krista L. Lanctôt,Lana S. Rothenburg,Amy P. Wong,Amy P. Wong,Jaclyn Cappell,Nathan Herrmann,Nathan Herrmann +8 more
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TLDR
The results strengthen the clinical evidence that AD is accompanied by an inflammatory response, particularly higher peripheral concentrations of IL-6, TNF-α, IL-1β, TGF-β,IL-12 and IL-18 and higher CSF concentrations of T GF-β.About:
This article is published in Biological Psychiatry.The article was published on 2010-11-15. It has received 866 citations till now.read more
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Dissertation
The genetic and functional basis of three inherited cutaneous and gastrointestinal diseases in humans
TL;DR: In this article, the authors propose a 3.3-approximation algorithm for the 3.1-GHz bandit-16.3 GHz frequency bandit model, and
Journal ArticleDOI
Seroprevalence of Toxocara canis and the parasitic effect on plasma cytokines in children aged 6 to 11 years in Saki-East local government area in Nigeria
TL;DR: The work revealed an overall seroprevalence of T. canis as 9.5% monoinfection and a significant increase in plasma TNFα and IL-10 in T.Canis monoinfected children compared with the control (P < 0.05).
Journal ArticleDOI
A Rational Insight into the Effect of Dimethyl Sulfoxide on TNF-α Activity
TL;DR: This study found that the sensitizing effect of actinomycin D on TNF-α-induced cell death depends upon the timing of these treatments and on the cell type, and will help to select an appropriate concentration of DMSO as a working solvent for the screening of water-insoluble T NF-α inhibitors.
Dissertation
Effects of acute exercise and voluntary freewheel exercise in mice on pro- inflammatory cytokines and markers of apoptosis in the hippocampus
TL;DR: This research consists of two experiments that were designed to explore the effects of physical activity on pro- and anti-inflammatory cytokines and apoptosis in the mouse hippocampus, a brain region implicated in learning, memory, and cognition.
Journal ArticleDOI
Anti-Inflammatory Properties of MSF, a Lactiplantibacillus plantarum K8 Lysate Fermented with Filipendula glaberrima Extract
TL;DR: Results show that probiotic lysates fermented with natural extracts such as F. glaberrima have higher anti-inflammatory efficacy than conventional probioticLysates or natural extracts.
References
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Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
Journal ArticleDOI
Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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