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Journal ArticleDOI

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2197-2223
TLDR
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account.
About: 
This article is published in The Lancet.The article was published on 2012-12-15. It has received 6861 citations till now. The article focuses on the topics: Disease burden & Disability-adjusted life year.

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Citations
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Journal ArticleDOI

Epidemiology of anxiety disorders: from surveys to nosology and back.

Dan J. Stein, +3 more
- 01 Jun 2017 - 
TL;DR: It is emphasized that anxiety disorders are the most prevalent of the psychiatric conditions, and that rather than merely contrasting cross-national prevalence in anxiety disorders, it is more productive to delineateCross-national themes that emerge about the epidemiology of these conditions.
Journal ArticleDOI

Outcomes associated with early post-traumatic osteoarthritis and other negative health consequences 3–10 years following knee joint injury in youth sport

Jackie L. Whittaker, +6 more
- 01 Jul 2015 - 
TL;DR: Preliminary evidence is provided that youth/young adults following sport-related knee injury report more symptoms and poorer function, and are at greater risk of being overweight/obese 3-10 years post-injury compared to matched uninjured controls.
Journal ArticleDOI

The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database.

Eden Sebbag, +5 more
- 01 Jun 2019 - 
TL;DR: The burden of MSK diseases increased significantly between 2000 and 2015 and is high in Europe, and these results are crucial to health professionals and policy makers to implement future health plan adjustments for MSk diseases.
Journal ArticleDOI

NLRP3 gene knockout blocks NF-κB and MAPK signaling pathway in CUMS-induced depression mouse model.

Wen-Jun Su, +12 more
- 30 Mar 2017 - 
TL;DR: These data proved that the NLRP3 inflammasome mediated CUMS‐induced depression‐like behavior and regulated CUMS'induced MAPK pathway and NF‐&kgr;B protein complex activation in depression mouse model.
Journal ArticleDOI

Road Traffic Injury Prevention Initiatives: A Systematic Review and Metasummary of Effectiveness in Low and Middle Income Countries.

Catherine A. Staton, +15 more
- 06 Jan 2016 - 
TL;DR: Legislation was the most common intervention evaluated with the best outcomes when combined with strong enforcement initiatives or as part of a multifaceted approach, and speed control is crucial to crash and injury prevention.
References
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Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
Book

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

Christopher J L Murray, +1 more
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
Journal ArticleDOI

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
TL;DR: Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
Journal ArticleDOI

Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study

Christopher J L Murray, +1 more
- 17 May 1997 - 
TL;DR: The three leading contributors to the burden of disease are communicable and perinatal disorders affecting children, and the substantial burdens of neuropsychiatric disorders and injuries are under-recognised.
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

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- 15 Dec 2012 - 

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

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The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

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