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Journal ArticleDOI

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2197-2223
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TLDR
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account.
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This article is published in The Lancet.The article was published on 2012-12-15. It has received 6861 citations till now. The article focuses on the topics: Disease burden & Disability-adjusted life year.

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Journal ArticleDOI

Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition.

TL;DR: The qualitative and quantitative differences between the microbial community profiles of cohorts of human volunteers from Sri Lanka with patent infection by one or more parasitic nematode species as well as that of uninfected subjects and of volunteers who had been subjected to regular prophylactic anthelmintic treatment are explored.
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Prevalence of diarrhoea and risk factors among children under five years old in Mbour, Senegal: a cross-sectional study

TL;DR: A high prevalence of diarrhoea in children under the age of five in Mbour, Senegal is found, with the highest prevalence occurring in the central and peri-central areas, underscoring the need for public health interventions to alleviate the burden of diarrhoeal diseases among vulnerable groups.
Journal ArticleDOI

Tooth loss in adults and income: Systematic review and meta-analysis.

TL;DR: The authors' results evidenced a relationship between income and tooth loss in adults and suggested that longitudinal studies with broader socioeconomic measures are encouraged.
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Short-term outcomes of platelet-rich plasma injection for treatment of osteoarthritis of the knee

TL;DR: It is suggested that PRP injection is more efficacious than HA injection and placebo in reducing symptoms and improving function and quality of life and has the potential to be the treatment of choice in patients with mild-to-moderate OA of the knee who have not responded to conventional treatment.
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Conservation of biodiversity as a strategy for improving human health and well-being

TL;DR: Current knowledge on biodiversity–zoonotic disease relationships is summarized, and a research plan is outlined to address the gaps in understanding for each of these four questions.
References
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Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
Book

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
Journal ArticleDOI

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
TL;DR: Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
Journal ArticleDOI

Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study

TL;DR: The three leading contributors to the burden of disease are communicable and perinatal disorders affecting children, and the substantial burdens of neuropsychiatric disorders and injuries are under-recognised.
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Stephen S Lim, +210 more
- 15 Dec 2012 -