Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Benzocaine-Loaded Polymeric Nanocapsules: Study of the Anesthetic Activities
Nathalie Ferreira Silva de Melo,Nathalie Ferreira Silva de Melo,Daniele Ribeiro de Araujo,Renato Grillo,Renato Grillo,Carolina Morales Moraes,Angélica Prado de Matos,Eneida de Paula,André Henrique Rosa,Leonardo Fernandes Fraceto,Leonardo Fernandes Fraceto +10 more
TL;DR: A comparison of different polymeric nanocapsules (NCs) prepared with the polymers poly(D,L-Lactide-co-glycolide), poly(L-lactide) (PLA), and poly(e-caprolactone) and used as carrier systems for the local anesthetic (LA) benzocaine (BZC) was performed in this article.
Journal ArticleDOI
Water retention and slow release studies of a salep-based hydrogel nanocomposite reinforced with montmorillonite clay
TL;DR: In this article, a slow-release NPK fertilizer formulation was prepared via insitu free radical graft polymerization of salep with an acrylic acid (AA) monomer in the presence of montmorillonite (MMT) and fertilizer.
Journal ArticleDOI
Eudragit S-100 coated sodium alginate microspheres of naproxen sodium: formulation, optimization and in vitro evaluation.
TL;DR: In this paper, a modified emulsification method followed by cross-linking with CaCl2, which was further coated with the pH dependent polymer Eudragit S-100 (2.5 or 5 %) to prevent drug release in the upper gastrointestinal environment.
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Micronization of ethosuximide using the rapid expansion of supercritical solution (RESS) process
TL;DR: In this paper, the effects of four process parameters on the particle formation of ethosuximide were investigated and it was observed that an operation at a higher extraction pressure, lower post-expansion temperature and smaller orifice nozzle diameter is favorable for the production of smaller ethosoximide particles while the effect of preexpansion temperatures is insignificant.
Journal ArticleDOI
Customized Therapeutic Surface Coatings for Dental Implants
Muhammad Sohail Zafar,Muhammad A. Fareed,Samiya Riaz,Muhammad Latif,Syed Rashid Habib,Zohaib Khurshid +5 more
TL;DR: Several strategies for local drug delivery and their limitations in dental implant coatings are highlighted as some of these concepts are yet to be applied in clinical settings due to the specific requirements of individual patients.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.