Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Modeling and Comparison of Dissolution Profiles of Diltiazem Modified-Release Formulations
TL;DR: In this paper, the authors compared dissolution profiles in simulated fasted and fed states and determined whether there is a change in the mechanism of drug release in diltiazem extended-release formulations.
Journal ArticleDOI
Improvement of anti-inflammatory and anti-angiogenic activity of berberine by novel rapid dissolving nanoemulsifying technique.
TL;DR: The development and characterization of self-nanoemulsifying drug delivery system (SNEDDS) of berberine in liquid as well as solid form with improved solubility, dissolution and in vivo therapeutic efficacy are described.
Journal ArticleDOI
Functionalized bimodal mesoporous silicas as carriers for controlled aspirin delivery
Lin Gao,Jihong Sun,Yuzhen Li +2 more
TL;DR: In this paper, a modified bimodal mesoporous silica with 3-aminopropyltriethoxysilane (3-AMT) was used as the aspirin carrier.
Journal ArticleDOI
In vitro release kinetics and bioavailability of gastroretentive cinnarizine hydrochloride tablet.
TL;DR: It was demonstrated that the floating tablet CNZ could be a 24-h sustained release formulation and the greater bioavailability of HP1 was due to its longer retention in the gastric environment of the test animal.
Journal ArticleDOI
Preparation and evaluation of clindamycin phosphate loaded chitosan/alginate polyelectrolyte complex film as mucoadhesive drug delivery system for periodontal therapy.
TL;DR: 3D structure of the drug loaded complex film was analyzed by Micro‐CT imaging and it was showed that using this method would be very advantageous for further studies about the investigation of complexation than the other imaging methods in order to determine the volume and the size of the formed complexes within the structure at the same time.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.