Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Tenofovir Containing Thiolated Chitosan Core/Shell Nanofibers: In Vitro and in Vivo Evaluations
Jianing Meng,Vivek Agrahari,Miezan J. Ezoulin,Chi Zhang,Sudhaunshu S. Purohit,Agostino Molteni,Daniel C. Dim,Nathan A. Oyler,Bi Botti C. Youan +8 more
TL;DR: Owing to their enhanced drug loading and preliminary safety profile, the TCS core/shell NFs are promising candidates for the topical delivery of HIV/AIDS microbicides such as tenofovir.
Journal ArticleDOI
Preparation and characterization of bio-organoclays using nonionic surfactant
Maria Liria Turco Liveri,Marcello Merli,Giuseppe Lazzara,Luciana Sciascia,Giuseppe Cavallaro,Ilaria Calabrese +5 more
TL;DR: In this article, the influence of two internal parameters, namely pH and surfactant/clay ratio, on the surfactants uptake ability by clay was investigated, and the adsorption mechanism was elucidated on the basis of complementary kinetic and equilibrium studies.
Journal ArticleDOI
Mesoporous silica core–shell composite functionalized with polyelectrolytes for drug delivery
TL;DR: In this paper, polyelectrolytes-coated silica particles (SiPs) with high surface area (1254 m2/g) have been synthesized for controlled release of ibuprofen (IBU) in aqueous dispersion.
Journal ArticleDOI
Design and evaluation of succinylated soy protein tablets as delayed drug delivery systems.
TL;DR: Succinylated soy protein tablets were thus gastroresistant, suggesting their use as excipients for controlled release of medicinal or nutraceutical agents.
Patent
Tamper resistant dosage form comprising inorganic salt
TL;DR: In this article, a pharmaceutical dosage form exhibiting a breaking strength of at least 500 N, a dosage form containing a pharmacologically active ingredient (A); an inorganic salt (B); and a polyalkylene oxide (C) having a weight average molecular weight of at at least 200,000 g/mol, wherein the content of the polyalkane oxide was at least 20 wt.-%, based on the total weight of the dosage form.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.