Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Microstructure-based mathematical modelling and spectroscopic imaging of tablet dissolution
TL;DR: A computer model was developed with the objective of modelling pharmaceutical tablet dissolution with non-swelling excipients and it was verified using Fourier Transform Infrared (FTIR) spectroscopic imaging and UV–visible spectroscopy.
Journal ArticleDOI
Preparation and characterization of celecoxib dispersions in soluplus(®): comparison of spray drying and conventional methods
TL;DR: It was concluded that SOL was a proper carrier to enhance the dissolution rate of CLX and at high SOL ratios the method of preparation of dispersed samples had no effect on dissolution rate, whilst at low SOL content spray drying was more efficient method.
Journal ArticleDOI
Immobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration.
TL;DR: It is demonstrated that the DBC/Col-p composite is a promising material for tissue engineering and regeneration.
Journal ArticleDOI
Ultrasound-Triggered Controlled Drug Delivery and Biosensing Using Silica Nanotubes
TL;DR: Observance of significant enhancement in direct electron transfer of Hb makes the SNTs also promising for application in biosensors and drug yield as function of time is found to be heavily dependent on the ultrasound impulse protocol.
Journal ArticleDOI
Development of a new method to assess nanocrystal dissolution based on light scattering.
Katharina Anhalt,Katharina Anhalt,Simon Geissler,Meike Harms,Meike Harms,Markus Weigandt,Gert Fricker +6 more
TL;DR: A noninvasive, sensitive and reproducible method is presented to assess nanocrystal dissolution based on light scattering to allow a straightforward experimental setup with high temporal resolution.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.