Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Preparation and characterization of repaglinide loaded ethylcellulose nanoparticles by solvent diffusion technique using high pressure homogenizer
TL;DR: In this article, a sustained release nanoparticles has been designed to maintain constant level of a drug in the patient's blood stream, which can increase patient compliance by reducing the number of dosage and incidence of side effects.
Journal ArticleDOI
Corrosion resistance and drug release profile of gentamicin-loaded polyelectrolyte multilayers on magnesium alloys: Effects of heat treatment.
TL;DR: The gentamicin-loaded multilayers have been constructed on Mg alloys through spin-assisted layer-by-layer (SLbL) assembly and heat treatment is applied for improving the corrosion resistance and prolonging the drug release profile.
Journal ArticleDOI
Fabrication of a nanoparticle-containing 3D porous bone scaffold with proangiogenic and antibacterial properties.
Juan L. Paris,Nuria Lafuente-Gómez,M. Victoria Cabañas,J. Román,Juan Manuel Peña,María Vallet-Regí +5 more
TL;DR: F multifunctional 3D porous scaffolds with a designed porosity exhibit a sustained cephalexin delivery adequate for inhibiting bacterial growth as well as release the proangiogenic molecule which induces blood vessel formation in chicken embryos grown ex ovo.
Journal ArticleDOI
Lyophilized insulin nanoparticles prepared from quaternized N-aryl derivatives of chitosan as a new strategy for oral delivery of insulin: in vitro, ex vivo and in vivo characterizations.
TL;DR: As the result of optimized physico-chemical properties, drug release rate, cytotoxicity profile, ex vivo permeation enhancement and increased in vivo absorption, nanoparticles prepared from N-aryl derivatives of chitosan can be considered as valuable method for the oral delivery of insulin.
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Development and optimization of transferrin-conjugated nanostructured lipid carriers for brain delivery of paclitaxel using Box-Behnken design.
TL;DR: Tf-PTX-NLCs showed higher cytotoxic activity compared to non-targeted NLCs and free drug and could potentially be exploited as a delivery system in brain cancer cells.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.