Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
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Journal ArticleDOI
Direct, differential-equation-based in-vitro-in-vivo correlation (IVIVC) method.
TL;DR: The present method can provide increased transparency, improved performance, and greater modelling flexibility by avoiding the integral transforms used in the existing deconvolution‐ or convolution‐based IVIVC models.
Reference EntryDOI
Vaginal Drug Delivery
TL;DR: The main features of vaginal anatomy, physiology, and histology related to drug delivery as well as vaginal drug delivery systems and their evaluation are discussed, current usage of the vagina as a route of drug administration, and promising strategies in this field.
Journal ArticleDOI
Controlled Release of Oral Tetrahydrocurcumin from a Novel Self-Emulsifying Floating Drug Delivery System (SEFDDS)
TL;DR: Self-emulsifying floating drug delivery system that resulted in improved solubility, dissolution, and controlled release of the poorly water-soluble tetrahydrocurcumin (THC) can be a useful alternative for the strategic development of oral solid lipid-based formulations.
Journal ArticleDOI
Kinetic models for the release of the anticancer drug doxorubicin from biodegradable polylactide/metal oxide-based hybrids.
TL;DR: In this work, polylactide (PLA), doxorubicin (DOX), and metal oxide (MO) spheres were synthesised using the solvent-evaporation technique and were tested for sustained drug release and the potential for PLA use as a carrier was ascertained.
Journal ArticleDOI
A systematic physicochemical investigation on solubilization and in vitro release of poorly water soluble oxcarbazepine drug in pluronic micelles
TL;DR: In this article, the solubilization of hydrophobic drug oxcarbazepine (OXC) in different pluronics viz. F108, F127 and P84 have been studied employing state-of-the-art techniques.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.