Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Non-linear mixed effects models for the evaluation of dissolution profiles.
TL;DR: The use of non-linear mixed effects models to describe dissolution data has been evaluated and a theoretical part is included to introduce this approach to scientists who are not familiar with this type of statistics.
Journal ArticleDOI
Pickering emulsions for dermal delivery
TL;DR: In this article, the stability, structural and dermal delivery characteristics of Pickering emulsions composed of medium chain triglycerides, hydrophilic nanoparticles ~ 50 nm and lipophilic amphiphiles in the oil phase were analyzed.
Journal ArticleDOI
Monolayer grafting of aminosilane on magnetic nanoparticles: An efficient approach for targeted drug delivery system.
Rushikesh P. Dhavale,P.P. Waifalkar,Apoorva Sharma,Subasa C. Sahoo,Pratap Kollu,Pratap Kollu,Ashok D. Chougale,Dietrich R. T. Zahn,Georgeta Salvan,Pramod S. Patil,P.B. Patil +10 more
TL;DR: This work reports direct functionalization of MNPs with (3-Aminopropyl)triethoxysilane (APTES) which preserves the magnetization and can be extended to other biomedical applications where higher magnetization is desired.
Journal ArticleDOI
Sucrose esters with various hydrophilic-lipophilic properties : novel controlled release agents for oral drug delivery matrix tablets prepared by direct compaction
K. Chansanroj,G. Betz +1 more
TL;DR: The ability to improve the tableting properties as well as sustain the drug release rate of the highly soluble model drug via gelation of SE highlights SE as promising controlled release regulators for direct compacted matrix tablets comprising drugs with various solubilities according to the Biopharmaceutics Classification System.
Journal ArticleDOI
Cocrystal habit engineering to improve drug dissolution and alter derived powder properties.
TL;DR: The aim of this work was to engineer SDM : 4‐ASA cocrystals with different habits to investigate the effect on dissolution, and the derived powder properties of flow and compaction.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.