Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
The morphology of salt crystals affects the perception of saltiness
TL;DR: Crystal morphology may be a variable to consider to achieve sodium reduction while maintaining salt intensity in order to correlate the findings with the perception of saltiness over time.
Journal ArticleDOI
Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printing.
Georgios K. Eleftheriadis,Paraskevi Kyriaki Monou,Nikolaos Bouropoulos,Johan Boetker,Jukka Rantanen,Jette Bredahl Jacobsen,Ioannis S. Vizirianakis,Dimitrios G. Fatouros +7 more
TL;DR: This proof-of-concept study provides an alternative formulation approach of mucoadhesive buccal films, intended for the treatment of local oromucosal diseases or systemic drug delivery.
Journal ArticleDOI
Masking the Bitter Taste of Injectable Lidocaine HCl Formulation for Dental Procedures
TL;DR: The taste evaluation study indicated that HP-β-CD (1:1 and 1:2 M ratios) significantly improved the bitter taste of LID injectable formulation, and inclusion complex in the 1:1 M ratio with 0.09% sodium saccharin was considered to be optimum in masking the bitter tasted LID.
Journal ArticleDOI
Evaluation of acetylated moth bean starch as a carrier for controlled drug delivery.
TL;DR: A new hydrophobic polymer is synthesized using acetylation of native moth bean starch for controlled release excipient for pharmaceutical formulation development and the results revealed that the acetylated mothbean starch can be used as controlled release polymer.
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Sintering of wax for controlling release from pellets
TL;DR: In vitro drug release profiles indicated an increase in drug release retardation with increasing carnauba wax concentration, and sintered pellets had a higher hydrophobicity than did the unsintered pellets.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.