Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Fusion Method for Solubility and Dissolution Rate Enhancement of Ibuprofen Using Block Copolymer Poloxamer 407
TL;DR: This work shows the effect of eutectic formation and micellar solubilization between ibuprofen and poloxamer at the given ratios on its solubility and dissolution rate enhancement.
Journal ArticleDOI
Recrystallization and micronization of sulfathiazole by applying the supercritical antisolvent technology
TL;DR: In this article, the authors investigated the effects of different solvents, temperature and pressure on sulfathiazole particle formation using the supercritical antisolvent (SAS) technology.
Journal ArticleDOI
Formulation optimization and evaluation of fast dissolving film of aprepitant by using design of experiment
TL;DR: In this paper, fast dissolving films (FDF) of aprepitant used in the prevention and treatment of chemotherapy-induced nausea and vomiting were prepared using solvent casting method and optimized employing central composite design considering two independent variables film forming polymer and PEG 400.
Journal ArticleDOI
Deproteinized natural rubber film forming polymeric solutions for nicotine transdermal delivery
Wiwat Pichayakorn,Jirapornchai Suksaeree,Prapaporn Boonme,Thanaporn Amnuaikit,Wirach Taweepreda,Garnpimol C. Ritthidej +5 more
TL;DR: Film forming polymeric solutions could be developed for transdermal nicotine delivery systems using DNRL blended with MC, PVA, or SAG together with dibutylphthalate or glycerine used as plasticizers.
Journal ArticleDOI
Magnetic responsive of paclitaxel delivery system based on SPION and palmitoyl chitosan
Mona Mansouri,Masoumeh Haghbin Nazarpak,Atefeh Solouk,Somaye Akbari,Mohammad Mahdi Hasani-Sadrabadi +4 more
TL;DR: Findings indicate that the resultant nanoparticles may serve as a biocompatible and biodegradable carrier for the precise delivery of powerful cytotoxic anticancer agents such as PTX.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.