Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Kinetics and Antioxidant Capacity of Proanthocyanidins Encapsulated in Zein Electrospun Fibers by Cyclic Voltammetry.
TL;DR: Zein-PA fibers showed a good controlled release toward PA, and the predominant release of PA from fibers was Fickian diffusion, which could be well described by first-order model and Hixson-Crowell model.
Journal ArticleDOI
Microencapsulation of β-Carotene Based on Casein/Guar Gum Blend Using Zeta Potential-Yield Stress Phenomenon: an Approach to Enhance Photo-stability and Retention of Functionality.
TL;DR: Minimal photolytic degradation upon encapsulation of β-carotene addressed the challenge regarding photo-stability ofβ- carotene as confirmed via mass spectroscopy.
Journal ArticleDOI
Floating drug delivery of a locally acting H2-antagonist: an approach using an in situ gelling liquid formulation.
TL;DR: Analysis of the release pattern showed that the drug release from in situ gel followed a diffusion mechanism, which significantly affected the formulation viscosity, floating behavior and in vitro drug release.
Journal ArticleDOI
Hydroxyapatite nanorods, hydrochar, biochar, and zeolite for controlled-release urea fertilizers
TL;DR: In this paper, the authors investigated the nitrogen release pattern of urea-impregnated biochar (UB), hydrochar (UH), UZ, and U-HAP in water and a calcareous waterlogged soil.
Journal ArticleDOI
Use of Physiologically Based Pharmacokinetic Models Coupled with Pharmacodynamic Models to Assess the Clinical Relevance of Current Bioequivalence Criteria for Generic Drug Products Containing Ibuprofen
TL;DR: Current bioequivalent guidance might be unnecessarily restrictive for ibuprofen products, according to the point estimate for the ratios T/R, which is well below the bioequivalence limits.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.