Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
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Amphiphilic chitosan-grafted-functionalized polylactic acid based nanoparticles as a delivery system for doxorubicin and temozolomide co-therapy
TL;DR: Results showed the continuous release of drugs without an initial burst in different physiological media as a carrier for the controlled release and co-release of two DNA alkylating drugs: doxorubicin and temozolomide.
Journal ArticleDOI
Design and evaluation of gastroretentive levofloxacin floating mini-tablets-in-capsule system for eradication of Helicobacter pylori.
TL;DR: LVF floating mini-tablets based on HPMC K100M is a promising formulation for eradication of H. pylori, and the optimized formula F1 offered the best controlled drug release along with floating lag time <1 s and total floating time >24 h.
Journal ArticleDOI
Tinidazole functionalized homogeneous electrospun chitosan/poly (ε-caprolactone) hybrid nanofiber membrane: Development, optimization and its clinical implications
Gayasuddin Khan,Sarita Kumari Yadav,Ravi R. Patel,Nagendra Kumar,Monika Bansal,Brahmeshwar Mishra +5 more
TL;DR: Preliminary clinical trials on patients proved therapeutic efficacy of the developed nanofiber membrane by eliciting a significant (p<0.05) decrease in clinical markers of periodontitis.
Journal ArticleDOI
Development and In Vitro-In Vivo Evaluation of Polymeric Implants for Continuous Systemic Delivery of Curcumin
TL;DR: Curcumin implants developed using poly (ε-caprolactone) as the polymeric matrix were able to release curcumin for long duration and to modulate liver phase I and phase II enzymes, demonstrating cur cumin’s biological efficacy delivered via this delivery system.
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Foliage adhesion and interactions with particulate delivery systems for plant nanobionics and intelligent agriculture
Renato Grillo,Bruno D. Mattos,Debora Ribeiro Antunes,Mariana M.L. Forini,Fazel Abdolahpur Monikh,Orlando J. Rojas,Orlando J. Rojas +6 more
TL;DR: This review introduces recent breakthroughs in nano-enabled agriculture, including pesticide delivery as well as genetic modification and the engineering of nanoparticles for application in living materials, and offers a critical discussion on the physico-chemistry of adhesion of nanoparticle to vegetal tissue, their uptake and translocation in and within plants.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.