Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Design and evaluation of polymeric coated minitablets as multiple unit gastroretentive floating drug delivery systems for furosemide.
Lingam Meka,Bhaskar Kesavan,Venkatasimhadri Naidu Kalamata,Chandra Mohan Eaga,Suresh Bandari,Venkateswarlu Vobalaboina,Madhusudan Rao Yamsani +6 more
TL;DR: The rapid floating and the controlled release properties were achieved in this present study.
Journal ArticleDOI
Hot melt extrusion paired fused deposition modeling 3D printing to develop hydroxypropyl cellulose based floating tablets of cinnarizine
TL;DR: Hot melt extrusion was coupled with 3D printing to develop a unique gastro retentive dosage form to personalize treatment of cinnarizine or other narrow absorption window drugs to meet individual patient needs.
Journal ArticleDOI
Solid solubility of antilipemic agents and micronization of gemfibrozil in supercritical carbon dioxide
TL;DR: In this article, the solubilities of three antilipemic agents of clofibric acid, fenofibrate and gemfibrozil in supercritical carbon dioxide were measured using a semi-flow apparatus.
Journal ArticleDOI
Potato starch‑blended alginate beads for prolonged release of tolbutamide: Development by statistical optimization and in vitro characterization
TL;DR: In this paper, the authors investigated the development and optimization of novel beads of potato starch-alginate blend containing tolbutamide by ionotropic gelation using 32 factorial design, which exhibited 85.57 ± 3.24% drug encapsulation efficiency and 50.42 ± 2.18% drug release after 8 h.
Journal ArticleDOI
Core-shell microcapsules of solid lipid nanoparticles and mesoporous silica for enhanced oral delivery of curcumin.
TL;DR: Findings suggest that organic core-silica shell microcapsules are promising drug delivery systems with enhanced bioavailability for poorly soluble drugs.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.