Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Journal ArticleDOI
Significant delivery of tacrine into the brain using magnetic chitosan microparticles for treating Alzheimer's disease.
Barnabas Wilson,Malay K. Samanta,Kumaraswamy Santhi,Kokilampal Perumal Sampath Kumar,Muthu Ramasamy,B Suresh +5 more
TL;DR: An attempt was made to target the anti-Alzheimer's drug tacrine in the brain by using magnetic chitosan microparticles, which significantly increased the concentration of tacrineIn the brain in comparison with the free drug.
Journal ArticleDOI
Films loaded with insulin-coated nanoparticles (ICNP) as potential platforms for peptide buccal delivery
TL;DR: ICNP-loaded ERL formulations were found to be more effective in terms of film performance and insulin permeation through the human buccal mucosa model, and thus are a promising delivery system for buCCal administration of a peptide such as insulin.
Journal ArticleDOI
pH-controlled delivery of curcumin from a compartmentalized solid lipid nanoparticle@mesostructured silica matrix
TL;DR: The meso-macrostructured silica matrix templated by SLNs appears thus as a promising drug delivery system for pH-responsive controlled release.
Journal ArticleDOI
Investigating the effect of tetracycline addition on nanocomposite hydrogels based on polyvinyl alcohol and chitosan nanoparticles for specific medical applications.
TL;DR: N nanocomposite hydrogel containing 5% of tetracycline can be suggested as a good candidate for wound dressing and novel drug delivery systems such as colon-specific drugs.
Journal ArticleDOI
Harnessing artificial intelligence for the next generation of 3D printed medicines.
Moe Elbadawi,Laura E. McCoubrey,Francesca K.H. Gavins,Jun Jie Ong,Alvaro Goyanes,Alvaro Goyanes,Simon Gaisford,Abdul Basit,Abdul Basit +8 more
TL;DR: In this article, a pharmaceutical 3D printing (3DP) based Internet of Things (IoT) is proposed to accelerate the use of pharmaceutical 3DP in clinical settings and drive the global movement towards personalised medicine and Industry 4.0.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.