Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TLDR
Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2001-05-01. It has received 4794 citations till now. The article focuses on the topics: Dissolution testing & Dosage form.read more
Citations
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Mass transfer coefficient measurement during brine flush in a CO2-filled packed bed by X-ray CT scanning
TL;DR: In this article, the authors performed dynamic experiments to elucidate transport during brine injection into a gaseous CO 2 -filled packed bed using X-ray CT technology, and the results showed that the distribution was related to the pore structure of the packed bed and flow rates.
Journal ArticleDOI
Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles.
TL;DR: Camptothecin (CPT), a molecule that shows powerful anticancer activity, is still not used in clinic due to its high hydrophobicity and poor active form's stability, and the combination between poly(anhydride) nanoparticles and cyclodextrins was evaluated.
Journal ArticleDOI
Experimental and robust modeling approach for lead(II) uptake by alginate gel beads: influence of the ionic strength and medium composition.
Salvatore Cataldo,Antonio Gianguzza,Marcello Merli,Nicola Muratore,Daniela Piazzese,Maria Liria Turco Liveri +5 more
TL;DR: Differential Pulse Anodic Stripping Voltammetry (DP-ASV), has been systematically used to perform kinetic and equilibrium measurements over continuous time in a wide range of concentration and results obtained showed a relevant dependence on ionic strength, composition of ionic media, pH of solution and number of gel beads.
Journal ArticleDOI
Enhanced transdermal permeation and anti-inflammatory potential of phospholipids complex-loaded matrix film of umbelliferone: Formulation development, physico-chemical and functional characterization
Darshan R. Telange,Shivendra B. Nirgulkar,Milind J. Umekar,Arun T. Patil,Anil M. Pethe,Nikhil Bali +5 more
TL;DR: The obtained results showed that the present combined formulation system could be employed as a promising strategy for improving transdermal permeation of UMB.
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Influence of different viscosity grade ethylcellulose polymers on encapsulation and in vitro release study of drug loaded nanoparticles
TL;DR: In this paper, the authors developed a sustain release metformin hydrochloride nanoparticulate system and studied the effect of different viscosity grade ethylcellulose polymers on in-vitro characteristics of obtained nanoparticles.
References
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Book
The mathematics of diffusion
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this paper, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Book
Introduction to percolation theory
Dietrich Stauffer,Amnon Aharony +1 more
TL;DR: In this article, a scaling solution for the Bethe lattice is proposed for cluster numbers and a scaling assumption for cluster number scaling assumptions for cluster radius and fractal dimension is proposed.
Journal ArticleDOI
Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
Journal ArticleDOI
Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices
TL;DR: The analyses suggest that for the latter system the time required to release 50% of the drug would normally be expected to be approximately 10 per cent of that required to dissolve the last trace of the solid drug phase in the center of the pellet.