Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
Citations
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Journal ArticleDOI
Synthesis and in vivo toxicity assessment of CdSe:ZnS quantum dots functionalized with EDTA-Bis-Cysteamine
Narmada Bag,Narmada Bag,Rashi Mathur,Firasat Hussain,Namita Indracanti,Sweta Singh,Shivani Singh,Shivani Singh,Ram Prakash Chauhan,Krishna Chuttani,Anil Mishra +10 more
TL;DR: This study highlights a facile route for designing small homo-dimeric ligand functionalized quantum dots nano-conjugates with favourable biological properties, enhancing their potential to be used as multi-modal imaging/theranostic agents.
Book ChapterDOI
Toxicity of nanomaterials to biomedical applications— A review
R. Mala,A. S. Ruby Celsia +1 more
TL;DR: The application of nanomaterials in biomedical field and the toxic effect of nanamaterials on in vitro and in vivo system are discussed and the physicochemical characteristics of a nanommaterial that influences the absorption, distribution, metabolism, and excretion of nanmaterials are elaborated.
Proceedings ArticleDOI
Optical detection of brain tumors using quantum dots
Steven A. Toms,Hamid Daneshvar,Osman Muhammad,Heather M. Jackson,Michael A. Vogelbaum,Marcel P. Bruchez +5 more
TL;DR: PEGylated quantum dots are avidly phagocytized by macrophages and are taken up by liver, spleen and lymph nodes, and may serve as an optical adjunct to aid in the operative resection of gliomas.
Journal ArticleDOI
Light-induced noncovalent fixation of DNA and synthetic polyions on the surface of silicon single crystals
TL;DR: In this article, a simple method for fixing DNA and synthetic polyions on the surface of p and n type Si(100) single crystals was presented, and the results of fixation were checked and analyzed by atomic force microscopy (AFM).
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.