Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
Citations
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Book ChapterDOI
Imaging vasculature and lymphatic flow in mice using quantum dots.
Byron Ballou,Lauren A. Ernst,Susan Andreko,James A. J. Fitzpatrick,B. Christoffer Lagerholm,Alan S. Waggoner,Marcel P. Bruchez +6 more
TL;DR: Red- and near-infrared-emitting quantum dots provide excellent definition of vasculature, lymphoid organs, and lymph nodes draining both normal tissues and tumors.
Dissertation
Synthèse, stabilité et toxicité de quantum dots à coeur CdSe
TL;DR: Notre projet vise l'utilisation du seleniure de cadmium (CdSe) comme materiau modele afin d'etablir une correlation entre the structure chimique des nanoparticules, leur reactivite de surface, leurs (photo)stabilite and leur toxicite as discussed by the authors.
Journal ArticleDOI
Reduction of nonspecific binding for cellular imaging using quantum dots conjugated with vitamin E
TL;DR: The developed TPGS3350-QDs NPs could be a promising tool for molecular imaging such as in vivo cell trafficking studies and show good stability and dispersion in aqueous solutions.
Journal ArticleDOI
Comprehensive study of interaction between biocompatible PEG-InP/ZnS QDs and bovine serum albumin.
M.S. Sannaikar,Laxmi S. Inamdar,G. H. Pujar,M.N. Wari,Nafisa H. Balasinor,Sanjeev R. Inamdar +5 more
TL;DR: These studies principally show that tryptophan residues of BSA have preferable binding affinity towards PEG-InP/ZnS QDs surface and a blue shift in Trp fluorescence emission is a signature of conformational changes in its hydrophobic microenvironment.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.