Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
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Polysaccharide surface modified Fe3O4 nanoparticles for camptothecin loading and release.
TL;DR: The in vitro inhibition rate of CPT-loaded polysaccharide modified Fe(3)O(4) nanoparticles against 7721 liver cancer cell increased significantly in comparison with that of C PT-free drug.
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Review: three synthesis methods of CdX (X = Se, S or Te) quantum dots
TL;DR: Three methods for synthesis of heavy metal chalcogenide-based QDs for use in biomedical field are discussed, including aqueous synthesis technique using short-chain thiols as stabilising agents is a useful alternative to organometallic synthesis of CdSe, CdS and CdTe QDs.
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Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media
TL;DR: Results suggested that the cellular toxicological mechanism of Ag NPs might be related to the oxidative stress of cells by the generation of ROS, leading to mitochondria injury and induction of apoptosis, and implies that it is important to assess the physicochemical properties of NPs in the media where the biological toxicity tests are performed.
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Quantum dots: from fluorescence to chemiluminescence, bioluminescence, electrochemiluminescence, and electrochemistry.
TL;DR: An overview of quantum dots, a novel class of inorganic fluorochromes, and their potential, especially in biomolecules analysis, including fluorescence detection, chemiluminescent detection, bioluminescence detection, electrochemilumineinescence Detection, and electrochemical detection are given.
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Optical molecular imaging agents for cancer diagnostics and therapeutics.
TL;DR: Molecular characterization in combination with optical imaging provides a sensitive and specific method to detect and prevent the progression of precancerous lesions and proves useful in further unraveling the molecular origins of cancer.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.