Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
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Can nanotechnology potentiate photodynamic therapy
Ying-Ying Huang,Sulbha K. Sharma,Tianhong Dai,Hoon Chung,Anastasia Yaroslavsky,María García-Díaz,Julie Chang,Long Y. Chiang,Michael R. Hamblin +8 more
TL;DR: The title question, “can nanotechnology potentiate PDT?” is attempted to answer.
Journal ArticleDOI
Integrated Multifunctional Nanosystems for Medical Diagnosis and Treatment
Donglu Shi,Donglu Shi +1 more
TL;DR: A novel system is developed specifically for achieving simultaneous diagnosis and treatment of cancer, and polymeric‐based nanosystems are introduced with several novel features: they can be bio‐dissolved due to environmental pH and temperature fluctuations.
Journal ArticleDOI
In Vivo Mouse Imaging and Spectroscopy in Drug Discovery
Nicolau Beckmann,Rainer Kneuer,Hans Ulrich Gremlich,Harry Karmouty-Quintana,Harry Karmouty-Quintana,François-Xavier Blé,Matthias Müller +6 more
TL;DR: This paper aims to illustrate how micro‐computed tomography and micro‐positron emission tomography techniques may be used to obtain meaningful information for the phenotyping of transgenic mice and for the analysis of compounds in murine models of disease.
Quantum dot: magic nanoparticle for imaging, detection and targeting.
TL;DR: Quantum dots (QDs) are one of the nanoparticles that use in Imaging, Detection and Targeting and have unique chemical and physical properties due to their size and their highly compact structure.
Journal ArticleDOI
Multifunctional Nanoparticles for Dual Imaging
Zulqurnain Ali,Azhar Z. Abbasi,Feng Zhang,Paolo Arosio,Alessandro Lascialfari,Alessandro Lascialfari,Maria Francesca Casula,Alexander Wenk,Wolfgang G. Kreyling,R. Plapper,Michael Seidel,Reinhard Niessner,Jürgen Knöll,Andreas Seubert,Wolfgang J. Parak +14 more
TL;DR: Colloidal nanoparticles composed out of an inorganic core and a polymer shell, which can be synthesized to be fluorescent, magnetic, or radioactive, are discussed.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.