Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
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Proceedings ArticleDOI
Luminescent probes for optical in vivo imaging
Isabelle Texier,Véronique Josserand,Elisabeth Garanger,Elisabeth Garanger,Jesus Razkin,Zhao-Hui Jin,Pascal Dumy,Marie Favrot,Didier Boturyn,Jean-Luc Coll +9 more
TL;DR: The ability of the imaging fluorescence set-up developed in LETI to image the bio-distribution of molecular probes on short times after injection is demonstrated and new fluorescent probes based on this dye and a molecular delivery template (the RAFT molecule) can thus be envisioned.
Journal ArticleDOI
Detection of Epstein–Barr virus infection in cancer by using highly specific nanoprobe based on dBSA capped CdTe quantum dots
TL;DR: By using denatured bovine serum albumin molecules as multidentate ligands, surface-functionalized CdTe quantum dots (QDs) were synthesized and further evaluated for preparing fluorescent probes capable of detecting Epstein–Barr virus infection and revealed that the dBSA coating effectively improved the optical stability of the resulting QDs.
Journal ArticleDOI
Occupational medicine implications of engineered nanoscale particulate matter
TL;DR: Preliminary research indicates that in some cases nanoparticulate matter may be more toxic than other forms of the same or similar material.
Journal ArticleDOI
Imaging the cardiovascular system: seeing is believing.
TL;DR: The role of proper imaging system calibration and the potential importance of calibration in understanding biological tissues, such as the cardiovascular system, that continually undergo deformation in response to strain are examined.
Book ChapterDOI
Perspectives on Percutaneous Penetration of Nanomaterials
TL;DR: In this paper, the classic ten steps of percutaneous penetration are expanded to 15 perspectives from the perspective of nanoparticles and the potential risks of dermal exposure, and uncertainties regarding the impact of nanoscale materials would be helped by greater consistency in methodologies used to assess health risks.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.