Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
Citations
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Journal ArticleDOI
Highly luminescent blue-emitting In1−xGaxP@ZnS quantum dots and their applications in QLEDs with inverted structure
TL;DR: In this article, the authors presented a strategy to synthesize pure group III-V In1−xGaxP blue-emitting alloy cores in a noncoordinating solvent with dodecanethiol (C12SH).
Journal ArticleDOI
A nanoporous optically transparent CdS-pHEMA hybrid with high optical sensing capability to dielectric liquids
TL;DR: This work suggests that the transparent, nanoporous CdS-pHEMA hybrids can be used as highly efficient optical sensing materials.
Applications in Cancer
TL;DR: Developments in bioaffinity nanoparticle probes for molecular and cellular imaging, targeted nanoparticle drugs for cancer therapy, and integrated nanodevices for early cancer detec- tion and screening raise exciting opportunities for personalized oncology.
Journal ArticleDOI
Quantum dot conjugated saporin activates microglia and induces selective substantia nigra degeneration.
TL;DR: SNc neurons are found to be exceptionally vulnerable to QD-saporin and this suggests that this could be a novel targeted approach to model PD-like inflammatory pathology.
DissertationDOI
Theoretical and experimental studies on manipulation of fluorescence by gold nanoparticle: Application for molecular imaging
TL;DR: The effect of the properties listed above on the fluorescence output was theoretically analyzed for the fluorophores frequently used in biomedical studies.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.