Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
Citations
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Journal ArticleDOI
Current and Future Lymphatic Imaging Modalities for Tumor Staging
Ghulam Murtaza,Kuo Gao,Tiegang Liu,Imran Tariq,Ashif Sajjad,Muhammad Akram,Meiying Niu,Guokai Liu,Zahid Mehmood,Guihua Tian +9 more
TL;DR: Poor resolution and low sensitivity is a limitation of traditional lymphatic imaging modalities; thus new noninvasive approaches like nanocarriers, magnetic resonance imaging, positron-emission tomography, and quantum dots are advantageous.
Use Of Nano Particles And Nanocrystals In Drug Discovery
TL;DR: Because of their unique properties Nanocrystals (quantum dots) and other nanoparticles (gold colloids, nanobars, dendrimers and nanoshells) have been receiving a lot of attention for potential use in Therapeutics, Bioengineering and therapeutics drug discovery.
Book ChapterDOI
Future Clinical Applications of Molecular Imaging: Nanoparticles, Cellular Probes, and Imaging of Gene Expression
TL;DR: Computed tomography (CT), magnetic resonance (MR), and ultrasound (US) imaging have been at the forefront of anatomical imaging modalities and provide little information of the physiological, molecular, and biochemical basis of disease.
Journal ArticleDOI
Targeting of Somatostatin Receptors Using Fluorescent Nanoparticles
TL;DR: SST can deliver the nanoparticles to the targeted sites with high drug delivery efficacy in vitro due to decoration with SST, which relates to the specificity of the interaction with somatostatin receptor.
Journal Article
Upconverting Luminescence Imaging and Tomography for Biomedical Applications
Niclas Svensson,Can T. Xu +1 more
TL;DR: In this paper, it is shown that by replacing the traditional Stokes-shifted fluorophores with upconverting nanocrystals, it is possible to avoid the nuisance of autofluorescence.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.