Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
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Nanowire-Based Biosensors: From Growth to Applications
Pranav Ambhorkar,Zongjie Wang,Hyuongho Ko,Sangmin Lee,Kyo-in Koo,Keekyoung Kim,Dong-il Dan Cho +6 more
TL;DR: Nanowire is expected to lead significant improvement of biomedical sensor in the near future because of its enormous surface area-to-volume ratio and its applications for the detection of biomarker, virus, and DNA.
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Quantum dots hold promise for early cancer imaging and detection
Pericles Pericleous,Maria Gazouli,Anna Lyberopoulou,Spyros Rizos,Nikolaos Nikiteas,Efstathios P. Efstathopoulos +5 more
TL;DR: The current utilisation of QDs as well as their future prospective to decipher and confront cancer are described, with critical issues that need to be further examined.
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Interactive threats of nanoparticles to the biological system.
Ruchi Roy,Ruchi Roy,Sandeep Kumar,Anurag Tripathi,Mukul Das,Mukul Das,Premendra D. Dwivedi,Premendra D. Dwivedi +7 more
TL;DR: The present review provides updated information on the various aspects such as sources of production, effect of different physical properties, interaction with biological system and mechanisms of engineered nanoparticles induced toxicities.
Journal ArticleDOI
The application of Fe3O4 nanoparticles in cancer research: a new strategy to inhibit drug resistance.
Xuemei Wang,Renyun Zhang,Chunhui Wu,Yong-Yuan Dai,Min Song,Sebastian Gutmann,Feng Gao,Gang Lv,Jingyuan Li,Xiaomao Li,Zhiqun Guan,Degang Fu,Baoan Chen +12 more
TL;DR: A novel strategy to inhibit the multidrug resistance of the targeted tumor cells by combining the unique properties of tetraheptylammonium capped Fe(3)O(4) magnetic nanoparticles with the drug accumulation of anticancer drug daunorubicin is explored.
Journal ArticleDOI
Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media
Can T. Xu,Niclas Svensson,Johan Axelsson,Pontus Svenmarker,Gabriel Somesfalean,Guanying Chen,Huijuan Liang,Haichun Liu,Zhiguo Zhang,Stefan Andersson-Engels +9 more
TL;DR: It was found that imaging with highly efficient upconverting nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.